Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,667 questions · 21,760 findings · 2,177 reviews

No studies found 4,173 · 19.2%GRADE not reported 2,300 · 10.6%Very low 5,276 · 24.2%Low 5,764 · 26.5%Moderate 3,298 · 15.2%High 949 · 4.4%

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Comprehensive geriatric assessment (CGA) vs usual care

Serious adverse events (falls) Median · older people at risk of poor health outcomes

It is very uncertain whether comprehensive Geriatric Assessment changes serious adverse events (falls) Median compared with usual care (very low certainty).

1 finding from 1 review

Remote ischaemic preconditioning (RIPC) vs no RIPC

Perioperative mortality · people undergoing elective major vascular surgery

Remote ischaemic preconditioning (RIPC) showed no clear difference in perioperative mortality (within 1 month after operation) compared with no RIPC (moderate certainty).

1 finding from 1 review

Remote ischaemic preconditioning (RIPC) vs no RIPC

Myocardial infarction (0 to 30 days) · people undergoing elective major vascular surgery

Remote ischaemic preconditioning (RIPC) showed no clear difference in myocardial infarction (within 1 month after operation) compared with no RIPC (moderate certainty).

1 finding from 1 review

Remote ischaemic preconditioning (RIPC) vs no RIPC

Renal impairment (within 1 month after operation) · people undergoing elective major vascular surgery

Remote ischaemic preconditioning (RIPC) showed no clear difference in renal impairment (within 1 month after operation) compared with no RIPC (moderate certainty).

1 finding from 1 review

Remote ischaemic preconditioning (RIPC) vs no RIPC

Limb loss (within 1 month after operation) · people undergoing elective major vascular surgery

Remote ischaemic preconditioning (RIPC) showed no clear difference in limb loss (within 1 month after operation) compared with no RIPC (low certainty).

1 finding from 1 review

Preconception lifestyle advice on weight vs usual care or attention control

Adverse events ‐ Gestational diabetes · women with infertility and obesity

It is very uncertain whether preconception lifestyle advice on weight changes adverse events ‐ Gestational diabetes compared with routine care or attention control (very low certainty).

1 finding from 1 review