Findings

What do systematic reviews say?

1,822 questions · 1,891 findings · 321 reviews · Headline outcomes only

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No studies found 279 · 14.8%GRADE not reported 46 · 2.4%Very low 524 · 27.7%Low 571 · 30.2%Moderate 330 · 17.5%High 141 · 7.5%

Reablement vs usual home‐care

QoL · adults aged ≥ 65 years

1 finding from 1 review

Time‐limited home‐care reablement services for maintaining and improving the functional independence of older adults 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 249 participants
Very low

Impairment/ disability Unified Parkinson's Disease Rating Scale (UPDRS; change in global UPDRS score). Scale from: 0 to 199 (lower score means less impairment/disability) · Patients with idiopathic Parkinson's disease

1 finding from 1 review

Transcranial direct current stimulation (tDCS) for idiopathic Parkinson's disease 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 45 participants
Very low

tDCS vs sham tDCS

Off time Self assessment (logfile) Scale from: 0 to 72 (lower score means less impairment/disability) · Patients with idiopathic Parkinson's disease

1 finding from 1 review

Transcranial direct current stimulation (tDCS) for idiopathic Parkinson's disease 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 25 participants
Very low

tDCS vs sham tDCS

On time with dyskinesia Self assessment (logfile) Scale from: 0 to 72 (lower score means less impairment/disability) · Patients with idiopathic Parkinson's disease

1 finding from 1 review

Transcranial direct current stimulation (tDCS) for idiopathic Parkinson's disease 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 25 participants
Very low

tDCS vs sham tDCS

Activity Gait speed · Patients with idiopathic Parkinson's disease

1 finding from 1 review

Transcranial direct current stimulation (tDCS) for idiopathic Parkinson's disease 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 41 participants
Very low

tDCS vs sham tDCS

Acceptability: dropouts during intervention period Rate of dropouts and adverse events · Patients with idiopathic Parkinson's disease

1 finding from 1 review

Transcranial direct current stimulation (tDCS) for idiopathic Parkinson's disease 2016 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 101 participants
Very low

Psychological therapies vs tricyclic antidepressants (TCAs)

Short‐term improvement Scale used (range; lower is better): Clinical Global Impression (1 to 7) Agoraphobic Cognitions Questionnaire (1 to 70) Panic Disorder Severity Scale (0 to 28) Brief Scale for Anxiety (0 to 60) · adults with panic disorder

1 finding from 1 review

Psychological therapies versus pharmacological interventions for panic disorder with or without agoraphobia in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 414 participants
Moderate

Psychological therapies vs other antidepressants

Short‐term improvement Scale used (range; lower is better): Panic Disorder Severity Scale (0 to 28) Symptom Checklist‐90‐Revised Global Severity · adults with panic disorder

1 finding from 1 review

Psychological therapies versus pharmacological interventions for panic disorder with or without agoraphobia in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 27 participants
Moderate

Psychological therapies vs benzodiazepines

Anxiety (state) · adults with panic disorder

1 finding from 1 review

Psychological therapies versus pharmacological interventions for panic disorder with or without agoraphobia in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 89 participants
Very low

Psychological therapies vs antidepressants alone or antidepressants and benzodiazepines

Short‐term improvement Scale used (range; lower is better): panic frequency Clinical Global Impression (1 to 7) Agoraphobic Cognitive Questionnaire (1 to 70) Fear Questionnaire Agoraphobia Subscale (0 to 14) Brief Scale for Anxiety (0 to 60) STAI ... · adults with panic disorder

1 finding from 1 review

Psychological therapies versus pharmacological interventions for panic disorder with or without agoraphobia in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
11 studies · 638 participants
Low

Psychological therapies vs SSRI

1 finding from 1 review

Psychological therapies versus pharmacological interventions for panic disorder with or without agoraphobia in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 242 participants
Moderate

Skin grafts and tissue replacements vs placebo or usual care

Total incidence of lower limb amputations · people with diabetes and foot ulcers

It is very uncertain whether skin grafts and tissue replacements changes total incidence of lower limb amputations compared with placebo or standard care (very low certainty).

1 finding from 1 review

Skin grafting and tissue replacement for treating foot ulcers in people with diabetes 2016 · Cochrane Headline outcomes only
RR 0.43 [0.23, 0.81]
2 studies · 522 participants
Very low

Intervention not reported

Asthma control (ACQ) Scale 0 to 6; lower is better12 months · adults or children with asthma

1 finding from 1 review

Remote versus face‐to‐face check‐ups for asthma 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 146 participants
Moderate

CBT vs usual care

Asthma control · adults and adolescents with asthma

1 finding from 1 review

Cognitive behavioural therapy (CBT) for adults and adolescents with asthma 2016 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 95 participants
Low

CBT vs usual care

Unscheduled healthcare utilisation ‐ number of hospital or GP/ED visits · adults and adolescents with asthma

1 finding from 1 review

Cognitive behavioural therapy (CBT) for adults and adolescents with asthma 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 80 participants
Low

CBT vs usual care

Anxiety · adults and adolescents with asthma

1 finding from 1 review

Cognitive behavioural therapy (CBT) for adults and adolescents with asthma 2016 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 225 participants
Low

CBT vs usual care

Depression at endpoint · adults and adolescents with asthma

1 finding from 1 review

Cognitive behavioural therapy (CBT) for adults and adolescents with asthma 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 112 participants
Low

CBT vs usual care

Adherence · adults and adolescents with asthma

1 finding from 1 review

Cognitive behavioural therapy (CBT) for adults and adolescents with asthma 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 23 participants
Low

BIFEPRUNOX vs placebo

Mental state: 1. Mean change PANSS positive subscale (lower value = good) · patients with schizophrenia

1 finding from 1 review

Bifeprunox versus placebo for schizophrenia 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 549 participants
Low

BIFEPRUNOX vs placebo

Mental state: 2. Mean change PANSS negative subscale (lower value = good) · patients with schizophrenia

1 finding from 1 review

Bifeprunox versus placebo for schizophrenia 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 549 participants
Low