Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

643 questions · 671 findings · 87 reviews

No studies found 177 · 26.4%GRADE not reported 106 · 15.8%Very low 182 · 27.1%Low 114 · 17%Moderate 66 · 9.8%High 26 · 3.9%

Risk‐reducing salpingo‐oophorectomy (RRSO) vs no RRSO according to BRCA mutation status

Overall survival: BRCA1 only

It is very uncertain whether risk‐reducing salpingo‐oophorectomy (RRSO) changes overall survival: BRCA1 only compared with no RRSO according to BRCA mutation status (very low certainty).

1 finding from 1 review

Risk‐reducing salpingo‐oophorectomy (RRSO) vs no RRSO according to BRCA mutation status

Overall survival: BRCA2 only

It is very uncertain whether risk‐reducing salpingo‐oophorectomy (RRSO) changes overall survival: BRCA2 only compared with no RRSO according to BRCA mutation status (very low certainty).

1 finding from 1 review