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Evidence found and GRADE certainty

2,262 questions · 2,405 findings · 248 reviews · Headline outcomes only

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No studies found 507 · 21.1%GRADE not reported 93 · 3.9%Very low 657 · 27.3%Low 708 · 29.4%Moderate 387 · 16.1%High 53 · 2.2%

Complex information, support and training interventions vs inactive control (usual care care, attention control, waitlist)

Leaving the study early · Informal caregivers of people with dementia

Complex information, support and training interventions showed no clear difference in dropouts for any reason compared with usual treatment, waiting list or attention control informations (low certainty).

1 finding from 1 review

Complex information, support and training interventions vs inactive control (usual care care, attention control, waitlist)

Use of health and social resources · Informal caregivers of people with dementia

Complex information, support and training interventions showed no clear difference in use of health and social resources compared with usual treatment, waiting list or attention control informations (moderate certainty).

1 finding from 1 review

Lay health worker‐led psychological interventions vs usual care

Recovery from CMD ‐ intermediate term (1 to 6 months post intervention) Recovery defined by GDS ≤ 11a; HDRS < 7b; HDRS < 8c; PHQ‐9 < 6d; PHQ‐9 < 5 or 50% reduction from baselinee (RR > 1 denotes greater likelihood of recovery) · adults with common mental disorders

Lay health worker‐led psychological interventions may leads to higher recovery from CMDs ‐ intermediate term (1 to 6 months post… compared with usual care (low certainty).

1 finding from 1 review

Lay health worker‐led psychosocial interventions vs enhanced usual care

Depression recovery ‐ intermediate term (1 to 6 months post intervention) · women with perinatal depression

Lay health worker‐led psychosocial interventions may leads to higher recovery from depression ‐ intermediate term (1 to 6 months post… compared with enhanced usual care (low certainty).

1 finding from 1 review

Lay health worker‐led psychosocial interventions vs enhanced usual care

Depression symptoms ‐ intermediate term (1 to 6 months post intervention) GHQ‐12a; PHQ‐9d,e,f; self‐reporting questionnaireh (higher score = higher severity) · women with perinatal depression
1 finding from 1 review

Lay health worker‐led psychosocial interventions vs enhanced usual care

Functional impairment · women with perinatal depression

Lay health worker‐led psychosocial interventions showed no clear difference in functional impairment ‐ intermediate term (1 to 6 months post… compared with enhanced usual care (low certainty).

1 finding from 1 review

Lay health worker‐led psychological interventions vs usual care

Prevalence of CMDs ‐ intermediate term (1 to 6 months post intervention) Diagnosis defined by SRQ‐20 > 7b; PHQ‐9 ≥ 11d (RR < 1 denotes lower prevalence compared to control) · adults with common mental disorders

Lay health worker‐led psychological interventions may leads to lower prevalence of CMDs ‐ intermediate term (1 to 6 months post… compared with usual care (low certainty).

1 finding from 1 review

Lay health worker‐led psychosocial interventions vs enhanced usual care

Service utilisation ‐ maternal or child hospitalisations ‐ intermediate term (1 to 6 months post intervention) · women with perinatal depression

It is very uncertain whether lay health worker‐led psychosocial interventions changes service utilisation ‐ maternal or child hospitalisations ‐… compared with enhanced usual care (very low certainty).

1 finding from 1 review