The proportion of pressure ulcers healed · people with venous leg ulcers
Subfascial endoscopic perforator vein surgery (SEPS) + compression may leads to higher proportion with ulcers healed at 24 months compared with compression alone (low certainty).
1 finding from 1 review
Time to complete healing · people with venous leg ulcers
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Recurrence of ulcers · people with venous leg ulcers
It is very uncertain whether subfascial endoscopic perforator vein surgery (SEPS) + compression changes ulcer recurrence at 24 months compared with compression alone (very low certainty).
1 finding from 1 review
Quality of life · people with venous leg ulcers
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events · people with venous leg ulcers
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Pain · people with venous leg ulcers
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Overall survival · Patients with brain metastases
Whole brain radiation therapy (WBRT) + stereotactic radiosurgery (SRS) showed no clear difference in overall survival compared with WBRT (moderate certainty).
1 finding from 1 review
Disease‐specific survival · Patients with brain metastases
Whole brain radiation therapy (WBRT) + stereotactic radiosurgery (SRS) showed no clear difference in disease‐specific survival compared with WBRT (moderate certainty).
1 finding from 1 review
Local tumor control · Patients with brain metastases
Whole brain radiation therapy (WBRT) + stereotactic radiosurgery (SRS) probably leads to lower local tumor control compared with WBRT (moderate certainty).
1 finding from 1 review
Functionally independent survival (KPS) · Patients with brain metastases
Whole brain radiation therapy (WBRT) + stereotactic radiosurgery (SRS) showed no clear difference in functionally independent survival (KPS) compared with WBRT (moderate certainty).
1 finding from 1 review
Steroid use · Patients with brain metastases
Whole brain radiation therapy (WBRT) + stereotactic radiosurgery (SRS) may leads to lower steroid use compared with WBRT (low certainty).
1 finding from 1 review
Change in QoL SNOT‐20 · children and adults diagnosed with cystic fibrosis and chronic rhinosinusitis with nasal polyposis
1 finding from 1 review
FEV1 % predicted: absolute change from baseline · children and adults diagnosed with cystic fibrosis and chronic rhinosinusitis with nasal polyposis
1 finding from 1 review
Eradication of bacterial infection · children and adults diagnosed with cystic fibrosis and chronic rhinosinusitis with nasal polyposis
1 finding from 1 review
Clinical improvement(visual analogue scale) · children and adults diagnosed with cystic fibrosis and chronic rhinosinusitis with nasal polyposis
1 finding from 1 review
Pulmonary exacerbations · children and adults diagnosed with cystic fibrosis and chronic rhinosinusitis with nasal polyposis
1 finding from 1 review
All‐cause mortality · children and adults diagnosed with cystic fibrosis and chronic rhinosinusitis with nasal polyposis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Overall survivalNo. of participants: 2631(8 RCTs) · patients with newly diagnosed multiple brain metastases
WBRT and radiosurgery showed no clear difference in overall survivalNo. of participants: 358(2 RCTs) compared with WBRT (moderate certainty).
1 finding from 1 review
HR 0.61 [0.27, 1.39]
Studies not reported
Moderate
1‐Year overall brain control ratesNo. of participants: 400(3 RCTs) · patients with newly diagnosed multiple brain metastases
WBRT and radiosurgery leads to lower 1‐Year overall brain control ratesNo. of participants: 400(3 RCTs) compared with WBRT (high certainty).
1 finding from 1 review
HR 0.39 [0.25, 0.6]
Studies not reported
High
Adverse effectsNo. of participants: 1754(9 RCTs) · patients with newly diagnosed multiple brain metastases
1 finding from 1 review
no estimate extracted
Studies not reported
High