Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,271 questions · 1,326 findings · 329 reviews

No studies found 247 · 18.6%GRADE not reported 237 · 17.9%Very low 379 · 28.6%Low 285 · 21.5%Moderate 141 · 10.6%High 37 · 2.8%

Intervention not reported

One or more events of upper airway discomfort or injury: low risk of bias trials · improving conditions during tracheal intubation or direct laryngoscopy in adults and adolescents

The intervention led to higher one or more events of upper airway discomfort or injury: low risk of…; GRADE not reported.

1 finding from 1 review

Intervention not reported

One or more events of upper airway discomfort or injury: all trials · improving conditions during tracheal intubation or direct laryngoscopy in adults and adolescents

The intervention probably leads to higher one or more events of upper airway discomfort or injury: all trials (moderate certainty).

1 finding from 1 review

HALOPERIDOL vs chlorpromazine

Repeated need for rapid tranquillisation ‐ more than 1 injection · patients with psychosis‐induced aggression or agitation

It is very uncertain whether HALOPERIDOL changes repeated need for rapid tranquillisation ‐ more that 1 injection compared with OTHER ANTIPSYCHOTIC: b. CHLORPROMAZINE (very low certainty).

1 finding from 1 review

HALOPERIDOL vs OTHER ANTIPSYCHOTIC: c. DROPERIDOL

Repeated need for rapid tranquillisation ‐ more than 1 injection · psychosis‐induced aggression or agitation

HALOPERIDOL probably leads to higher repeated need for rapid tranquillisation ‐ more than 1 injection compared with OTHER ANTIPSYCHOTIC: c. DROPERIDOL (moderate certainty).

1 finding from 1 review

HALOPERIDOL vs OTHER ANTIPSYCHOTIC: j. ZUCLOPENTHIXOL ACETATE

Repeated need for rapid tranquillisation ‐ more than 3 injections · patients with psychosis‐induced aggression or agitation

It is very uncertain whether HALOPERIDOL changes repeated need for rapid tranquillisation ‐ more than 3 injections compared with OTHER ANTIPSYCHOTIC: k. ZUCLOPENTHIXOL ACETATE (very low certainty).

1 finding from 1 review

HALOPERIDOL vs lorazepam

Repeated need for rapid tranquillisation ‐ more than 1 injection · patients with psychosis‐induced aggression or agitation

It is very uncertain whether HALOPERIDOL changes repeated need for rapid tranquillisation more than 1 injection compared with BENZODIAZEPINE: b. LORAZEPAM (very low certainty).

1 finding from 1 review

Intervention not reported

Severity of ADHD (at study completion) WRAADDS scale (0 to 28), ADHD‐RS scale (0 to 54) or CAARS scale (0 to 48). On all scales, a higher score equates to more symptoms (at 6 weeks) · Adults with ADHD
1 finding from 1 review

Intervention not reported

Proportion of participants who lost two or more lines of best‐corrected visual acuity (BCVA) · participants aged 18‐60 years with myopia ranging in severity up to 12 diopters (D)

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Number of attempts at intubation and unsuccessful intubations assessed as unsuccessful or required more than 2 attempts at intubation · tracheal intubation in children (excluding neonates)

The intervention may leads to higher number of attempts at intubation and unsuccessful intubations… (low certainty).

1 finding from 1 review

Intervention not reported

Depression: Geriatric Depression Scale (GDS15) A 15‐item self‐report assessment used to identify depression in the elderly. A yes/no response is required for each item (score 0 or 1). Cummulative score: 0‐4 normal, 5‐9 Mild depression, 10‐15 More ... · adults with stroke
1 finding from 1 review