Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,036 questions · 1,100 findings · 261 reviews

No studies found 160 · 14.5%GRADE not reported 188 · 17.1%Very low 270 · 24.5%Low 303 · 27.5%Moderate 139 · 12.6%High 40 · 3.6%

Ciclopirox vs placebo

Failure to achieve complete resolution (combined for face and scalp) Clinical assessment · patients with seborrhoeic dermatitis

Ciclopirox probably leads to lower failure to achieve complete resolution (combined for face and scalp)… compared with placebo (moderate certainty).

1 finding from 1 review

Intervention not reported

Health‐related quality of life (health status) COPD Assessment Tool. Scale from 0 to 5; higher score indicates worse HRQoL Contains 10 questions with 5‐point Likert scale · individuals with stable bronchiectasis

The intervention showed no clear difference in health‐related quality of life (health status) COPD Assessment Tool.… (low certainty).

1 finding from 1 review

Intervention not reported

Quality of life Investigator global assessment Scale from 1 to 7 · patients with essential tremor
1 finding from 1 review

Tacrolimus 0.1% vs corticosteroids

Physician's assessment of global response of improvement, clear or excellent ‐ 6 weeks · people with atopic dermatitis

Tacrolimus 0.1% probably leads to higher physician's assessment of global response of improvement, clear or… compared with corticosteroids (moderate certainty).

3 findings from 1 review

Tacrolimus 0.03% vs corticosteroids

Physician's assessment of global response of improvement, clear or excellent ‐ 6 weeks · people with atopic dermatitis

Tacrolimus 0.03% probably leads to higher physician's assessment of global response of improvement, clear or… compared with corticosteroids (moderate certainty).

4 findings from 1 review
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Tacrolimus 0.03% vs corticosteroids

Participant's self‐assessment of global response of improvement: tacrolimus 0.03% 2x/day versus hydrocortisone acetate 1% 2x/day · people with atopic dermatitis

Tacrolimus 0.03% probably leads to higher participant's self‐assessment of global response of improvement:… compared with corticosteroids (moderate certainty).

1 finding from 1 review

Tacrolimus 0.03% vs Topical tacrolimus

Physician's assessment of global response of improvement · people with atopic dermatitis

Tacrolimus 0.03% leads to lower physician's assessment of global response of improvement, clear or… compared with tacrolimus 0.1% (high certainty).

1 finding from 1 review

Tacrolimus 0.03% vs pimecrolimus 1%

Physician's assessment of global response of improvement · people with atopic dermatitis

Tacrolimus 0.03% may leads to higher physician's assessment of global response of improvement compared with pimecrolimus 1% (low certainty).

1 finding from 1 review

Tacrolimus 0.1% vs corticosteroids

Participant's self‐assessment of global response of improvement · people with atopic dermatitis

Tacrolimus 0.1% may leads to higher participant's self‐assessment of global response of improvement compared with corticosteroids (low certainty).

1 finding from 1 review

Tacrolimus 0.1% vs pimecrolimus 1%

Physician's assessment of global response of improvement, clear or excellent ‐ 6 weeks · people with atopic dermatitis

Tacrolimus 0.1% probably leads to higher physician's assessment of global response of improvement, clear or… compared with pimecrolimus 1% (moderate certainty).

1 finding from 1 review

Infliximab vs placebo

Physician Global Assessment (Thongprasom score) · participants with hidradenitis suppurativa

Infliximab probably leads to higher physician global assessment compared with placebo (moderate certainty).

1 finding from 1 review

Intense pulsed light vs no treatment

Participant global assessment: satisfaction with treatment Questionnaire · participants with hidradenitis suppurativa

Intense pulsed light may leads to higher participant global assessment: satisfaction with treatment… compared with no treatment (low certainty).

1 finding from 1 review

Intense pulsed light vs no treatment

Participant global assessment: satisfaction with treatment ‐ axilla Questionnaire · participants with hidradenitis suppurativa

Intense pulsed light may leads to higher participant global assessment: satisfaction with treatment ‐ axilla… compared with no treatment (low certainty).

1 finding from 1 review

Intense pulsed light vs no treatment

Participant global assessment: satisfaction with treatment ‐ groin Questionnaire · participants with hidradenitis suppurativa

Intense pulsed light showed no clear difference in participant global assessment: satisfaction with treatment ‐ groin… compared with no treatment (low certainty).

1 finding from 1 review