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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
1,956 questions in 143 reviews · Musculoskeletal
current versionsNo studies 555 · 28.4%Ungraded 107 · 5.5%Very low 255 · 13%Low 555 · 28.4%Moderate 357 · 18.3%High 127 · 6.5%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Summary of findings table ‐ Exercise plus usual pharmacological care vs placebo plus usual pharmacological care Fatigue (FACIT‐Fatigue, score 0‐52, lower scores indicate less fatigue) · systemic lupus erythematosus Exercise as adjunctive therapy for systemic lupus erythematosus (2023) · Cochrane | no estimate extracted | 1 study · 17 participants | Low |
Summary of findings table ‐ Exercise plus usual pharmacological care vs usual pharmacological care alone Disease activity (SLEDAI scale, scores 0‐105, lower scores indicate less disease activity) · systemic lupus erythematosus Exercise as adjunctive therapy for systemic lupus erythematosus (2023) · Cochrane | no estimate extracted | 2 studies · 100 participants | Low |
Summary of findings table ‐ Exercise plus usual pharmacological care vs usual pharmacological care alone Quality of life ‐ not reported · systemic lupus erythematosus Exercise as adjunctive therapy for systemic lupus erythematosus (2023) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings table ‐ Exercise plus usual pharmacological care vs usual pharmacological care alone Pain (SF‐36 Bodily Pain domain, score 0‐100, lower scores indicate less pain) · systemic lupus erythematosus Exercise as adjunctive therapy for systemic lupus erythematosus (2023) · Cochrane | no estimate extracted | 1 study · 31 participants | Very low |
Summary of findings table ‐ Exercise plus usual pharmacological care vs usual pharmacological care alone Serious adverse events ‐ not reported · systemic lupus erythematosus Exercise as adjunctive therapy for systemic lupus erythematosus (2023) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings table ‐ Exercise plus usual pharmacological care vs usual pharmacological care alone Withdrawals due to any reason · systemic lupus erythematosus Exercise as adjunctive therapy for systemic lupus erythematosus (2023) · Cochrane | RR 0.92 [0.53, 1.6] | 6 studies · 235 participants | Very low |
Summary of findings table ‐ Exercise plus usual pharmacological care vs another intervention (education, joint aids, or relaxation) plus usual pharmacological care Fatigue (Fatigue Severity Scale, scores 0‐7, lower scores indicate less fatigue) · systemic lupus erythematosus Exercise as adjunctive therapy for systemic lupus erythematosus (2023) · Cochrane | no estimate extracted | 2 studies · 119 participants | Low |
Summary of findings table ‐ Exercise plus usual pharmacological care vs another intervention (education, joint aids, or relaxation) plus usual pharmacological care Functional capacity (SF‐36 Physical Function domain, score 0‐100, higher scores indicate better functional capacity) · systemic lupus erythematosus Exercise as adjunctive therapy for systemic lupus erythematosus (2023) · Cochrane | no estimate extracted | 3 studies · 182 participants | Low |
Summary of findings table ‐ Exercise plus usual pharmacological care vs another intervention (education, joint aids, or relaxation) plus usual pharmacological care Disease activity (SLEDAI scale, score 0‐105, lower scores indicate less disease activity) · systemic lupus erythematosus Exercise as adjunctive therapy for systemic lupus erythematosus (2023) · Cochrane | no estimate extracted | 4 studies · 184 participants | Moderate |
Summary of findings table ‐ Exercise plus usual pharmacological care vs another intervention (education, joint aids, or relaxation) plus usual pharmacological care Pain (VAS Pain scale, score 0‐10, lower scores indicate less pain) · systemic lupus erythematosus Exercise as adjunctive therapy for systemic lupus erythematosus (2023) · Cochrane | no estimate extracted | 2 studies · 121 participants | Low |
Summary of findings table ‐ Exercise plus usual pharmacological care vs another intervention (education, joint aids, or relaxation) plus usual pharmacological care Withdrawals due to any reason · systemic lupus erythematosus Exercise as adjunctive therapy for systemic lupus erythematosus (2023) · Cochrane | RR 0.89 [0.13, 5.94] | 7 studies · 317 participants | Very low |
Summary of findings table ‐ Exercise plus usual pharmacological care vs placebo plus usual pharmacological care Functional capacity (SF‐36 Function Capacity domain, score 0‐100, higher scores indicate better functional capacity) · systemic lupus erythematosus Exercise as adjunctive therapy for systemic lupus erythematosus (2023) · Cochrane | no estimate extracted | 1 study · 17 participants | Low |
Summary of findings table ‐ Exercise plus usual pharmacological care vs another intervention (education, joint aids, or relaxation) plus usual pharmacological care Serious adverse events ‐ not reported · systemic lupus erythematosus Exercise as adjunctive therapy for systemic lupus erythematosus (2023) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings table ‐ Exercise plus usual pharmacological care vs another intervention (education, joint aids, or relaxation) plus usual pharmacological care Quality of life ‐ not reported · systemic lupus erythematosus Exercise as adjunctive therapy for systemic lupus erythematosus (2023) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings table ‐ Exercise plus usual pharmacological care vs placebo plus usual pharmacological care Pain (SF‐36 Pain domain, score 0‐100, lower scores indicate less pain) · systemic lupus erythematosus Exercise as adjunctive therapy for systemic lupus erythematosus (2023) · Cochrane | no estimate extracted | 1 study · 17 participants | Low |
Summary of findings table ‐ Exercise plus usual pharmacological care vs placebo plus usual pharmacological care Disease activity ‐ not measured · systemic lupus erythematosus Exercise as adjunctive therapy for systemic lupus erythematosus (2023) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings table ‐ Exercise plus usual pharmacological care vs placebo plus usual pharmacological care Quality of life ‐ not measured · systemic lupus erythematosus Exercise as adjunctive therapy for systemic lupus erythematosus (2023) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings table ‐ Exercise plus usual pharmacological care vs placebo plus usual pharmacological care Serious adverse events ‐ not reported · systemic lupus erythematosus Exercise as adjunctive therapy for systemic lupus erythematosus (2023) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings table ‐ Exercise plus usual pharmacological care vs placebo plus usual pharmacological care Withdrawals due to any reason · systemic lupus erythematosus Exercise as adjunctive therapy for systemic lupus erythematosus (2023) · Cochrane | RR 2.73 [0.34, 22.16] | 1 study · 21 participants | Very low |
Summary of findings table ‐ Exercise plus usual pharmacological care vs usual pharmacological care alone Fatigue (Fatigue Severity Scale, score 1‐7, lower score indicates less fatigue) · systemic lupus erythematosus Exercise as adjunctive therapy for systemic lupus erythematosus (2023) · Cochrane | no estimate extracted | 2 studies · 104 participants | Low |
Summary of findings table ‐ Exercise plus usual pharmacological care vs usual pharmacological care alone Functional capacity (SF‐36 Physical Function domain, score 0‐100, higher scores indicate better functional capacity) · systemic lupus erythematosus Exercise as adjunctive therapy for systemic lupus erythematosus (2023) · Cochrane | no estimate extracted | 2 studies · 96 participants | Low |
Risedronate 5 mg/day vs placebo Clinical vertebral fractures · postmenopausal women at lower risk of fractures1 Risedronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women (2022) · Cochrane | no estimate extracted | NR | Low |
Risedronate 5 mg/day vs placebo Wrist fractures · pPostmenopausal women at higher risk of fractures1 Risedronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women (2022) · Cochrane | RR 0.64 [0.33, 1.24] | NR | Very low |
Risedronate 5 mg/day vs placebo Withdrawals due to adverse events · pPostmenopausal women at higher risk of fractures1 Risedronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women (2022) · Cochrane | RR 0.98 [0.9, 1.07] | NR | High |
Risedronate 5 mg/day vs placebo Serious adverse events · pPostmenopausal women at higher risk of fractures1 Risedronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women (2022) · Cochrane | RR 1 [0.94, 1.07] | NR | Moderate |
Risedronate 5 mg/day vs placebo Non‐vertebral fractures · postmenopausal women at lower risk of fractures1 Risedronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women (2022) · Cochrane | RR 0.54 [0.22, 1.35] | NR | Very low |
Risedronate 5 mg/day vs placebo Hip fractures · postmenopausal women at lower risk of fractures1 Risedronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women (2022) · Cochrane | no estimate extracted | NR | Low |
Risedronate 5 mg/day vs placebo Wrist fractures · postmenopausal women at lower risk of fractures1 Risedronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women (2022) · Cochrane | RR 0.48 [0.03, 7.5] | NR | Low |
Risedronate 5 mg/day vs placebo Withdrawals due to adverse events · postmenopausal women at lower risk of fractures1 Risedronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women (2022) · Cochrane | RR 0.67 [0.38, 1.18] | NR | Low |
Risedronate 5 mg/day vs placebo Serious adverse events · postmenopausal women at lower risk of fractures1 Risedronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women (2022) · Cochrane | RR 0.74 [0.42, 1.3] | NR | Very low |
Risedronate 5 mg/day vs placebo Clinical vertebral fractures · pPostmenopausal women at higher risk of fractures1 Risedronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women (2022) · Cochrane | no estimate extracted | NR | Low |
Risedronate 5 mg/day vs placebo Non‐vertebral fractures · pPostmenopausal women at higher risk of fractures1 Risedronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women (2022) · Cochrane | RR 0.8 [0.72, 0.9] | NR | Moderate |
Risedronate 5 mg/day vs placebo Hip fractures · pPostmenopausal women at higher risk of fractures1 Risedronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women (2022) · Cochrane | RR 0.73 [0.56, 0.94] | NR | Low |
Summary of findings table ‐ Exercise interventions vs usual care with or without sham interventions Functional ability: independence with activities of daily living at discharge from hospital · acutely hospitalised medical patients Exercise for acutely hospitalised older medical patients (2022) · Cochrane | no estimate extracted | 16 studies · 5174 participants | Low |
Summary of findings table ‐ Rehabilitation‐related activity interventions vs usual care with or without sham interventions Incidence of new delirium during hospitalisation · acutely hospitalised older medical patients Exercise for acutely hospitalised older medical patients (2022) · Cochrane | RR 0.86 [0.3, 2.5] | 2 studies · 732 participants | Very low |
Summary of findings table ‐ Rehabilitation‐related activity interventions vs usual care with or without sham interventions Falls during hospitalisation · acutely hospitalised older medical patients Exercise for acutely hospitalised older medical patients (2022) · Cochrane | RR 1.33 [0.3, 5.84] | 1 study · 250 participants | Ungraded |
Summary of findings table ‐ Rehabilitation‐related activity interventions vs usual care with or without sham interventions Quality of life at discharge from hospital · acutely hospitalised older medical patients Exercise for acutely hospitalised older medical patients (2022) · Cochrane | no estimate extracted | 1 study · 350 participants | Ungraded |
Summary of findings table ‐ Rehabilitation‐related activity interventions vs usual care with or without sham interventions Medical deterioration during hospitalisation · acutely hospitalised older medical patients Exercise for acutely hospitalised older medical patients (2022) · Cochrane | RR 0.86 [0.3, 2.5] | 2 studies · 732 participants | Very low |
Summary of findings table ‐ Rehabilitation‐related activity interventions vs usual care with or without sham interventions Participant global assessment of success · acutely hospitalised older medical patients Exercise for acutely hospitalised older medical patients (2022) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Summary of findings table ‐ Structured exercise interventions vs usual care with or without sham interventions Functional ability: independence with activities of daily living at discharge from hospital · acutely hospitalised older medical patients Exercise for acutely hospitalised older medical patients (2022) · Cochrane | no estimate extracted | 5 studies · 648 participants | Low |
Summary of findings table ‐ Structured exercise interventions vs usual care with or without sham interventions Functional ability: functional mobility at discharge from hospital · acutely hospitalised older medical patients Exercise for acutely hospitalised older medical patients (2022) · Cochrane | no estimate extracted | 2 studies · 416 participants | Very low |
Summary of findings table ‐ Structured exercise interventions vs usual care with or without sham interventions Functional ability: new incidence of delirium during hospitalisation · acutely hospitalised older medical patients Exercise for acutely hospitalised older medical patients (2022) · Cochrane | no estimate extracted | 1 study · 100 participants | Ungraded |
Summary of findings table ‐ Structured exercise interventions vs usual care with or without sham interventions Quality of life at discharge from hospital · acutely hospitalised older medical patients Exercise for acutely hospitalised older medical patients (2022) · Cochrane | no estimate extracted | 1 study · 76 participants | Ungraded |
Summary of findings table ‐ Structured exercise interventions vs usual care with or without sham interventions Falls during hospitalisation · acutely hospitalised older medical patients Exercise for acutely hospitalised older medical patients (2022) · Cochrane | RR 0.76 [0.23, 2.53] | 3 studies · 542 participants | Low |
Summary of findings table ‐ Exercise interventions vs usual care with or without sham interventions Functional ability: functional mobility at discharge from hospital · acutely hospitalised medical patients Exercise for acutely hospitalised older medical patients (2022) · Cochrane | no estimate extracted | 8 studies · 2369 participants | Very low |
Summary of findings table ‐ Structured exercise interventions vs usual care with or without sham interventions Medical deterioration during hospitalisation · acutely hospitalised older medical patients Exercise for acutely hospitalised older medical patients (2022) · Cochrane | RR 2.56 [0.48, 13.54] | 2 studies · 200 participants | Very low |
Summary of findings table ‐ Structured exercise interventions vs usual care with or without sham interventions Participant global assessment of success · acutely hospitalised older medical patients Exercise for acutely hospitalised older medical patients (2022) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Summary of findings table ‐ Progressive resistance exercise interventions vs usual care with or without sham interventions Functional ability: independence with activities of daily living at discharge from hospital · acutely hospitalised older medical patients Exercise for acutely hospitalised older medical patients (2022) · Cochrane | no estimate extracted | 7 studies · 1688 participants | Low |
Summary of findings table ‐ Progressive resistance exercise interventions vs usual care with or without sham interventions Functional ability: functional mobility at discharge from hospital · acutely hospitalised older medical patients Exercise for acutely hospitalised older medical patients (2022) · Cochrane | no estimate extracted | 5 studies · 978 participants | Very low |
Summary of findings table ‐ Progressive resistance exercise interventions vs usual care with or without sham interventions Functional ability: new incidence of delirium during hospitalisation · acutely hospitalised older medical patients Exercise for acutely hospitalised older medical patients (2022) · Cochrane | RR 0.96 [0.55, 1.68] | 4 studies · 1256 participants | Low |