Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

63 questions · 63 findings · 19 reviews · Neonatal

No studies found 9 · 14.3%GRADE not reported 5 · 7.9%Very low 18 · 28.6%Low 23 · 36.5%Moderate 8 · 12.7%High 0 · 0%

Supine midline head position vs any other supine head position

Retinopathy of prematurity, > stage 3 · very preterm infants with or at risk of germinal matrix‐intraventricular haemorrhage in preterm infants

It is very uncertain whether supine midline head position changes retinopathy of prematurity, > stage 3 compared with any other supine head position (very low certainty).

1 finding from 1 review

Supine midline head position vs any other supine head position

Long‐term neurodevelopmental outcome ‒not reported · very preterm infants with or at risk of germinal matrix‐intraventricular haemorrhage in preterm infants

The review found no eligible studies for this question.

1 finding from 1 review

Supine midline head position vs any other supine head position

Major neurodevelopmental disability ‒not reported · very preterm infants with or at risk of germinal matrix‐intraventricular haemorrhage in preterm infants

The review found no eligible studies for this question.

1 finding from 1 review

Supine midline head position vs any other supine head position

Cerebellar haemorrhage on brain ultrasound ‐ not reported · very preterm infants with or at risk of germinal matrix‐intraventricular haemorrhage in preterm infants

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

PIPP score during drug infusion Range of scale 0‐21 for infants < 28 weeks' PMA and 0‐18 for infants > 36 weeks' PMA. Lower score = less pain (Stevens 1996) · neonates requiring intubation and ventilation

The intervention showed no clear difference in PIPP score during drug infusion Range of scale 0‐21 for infants < 28… (moderate certainty).

1 finding from 1 review

Intervention not reported

Poor neurological outcome by 28 days' postnatal age · neonates requiring intubation and ventilation

The intervention showed no clear difference in poor neurological outcome by 28 days' postnatal age (moderate certainty).

1 finding from 1 review

Intervention not reported

PIPP score during drug infusion Range of scale 0‐21 for infants < 28 weeks' PMA and 0‐18 for infants > 36 weeks' PMA. Lower score = less pain (Stevens 1996) · neonates requiring intubation and ventilation

The intervention showed no clear difference in PIPP score during drug infusion Range of scale 0‐21 for infants < 28… (moderate certainty).

1 finding from 1 review