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Evidence found and GRADE certainty

383 questions · 414 findings · 46 reviews · Hypertension

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No studies found 15 · 3.6%GRADE not reported 31 · 7.5%Very low 80 · 19.3%Low 148 · 35.7%Moderate 116 · 28%High 24 · 5.8%

Intensive periodontal treatment (subgingival SRP with or without other periodontal treatment) vs Supra-gingival scaling

Heart rate · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension

The review found no eligible studies for this question.

1 finding from 1 review
  • Effect of periodontal treatments on blood pressure 2021 · Cochrane All outcomes
    Heart rate was reported only by Higashi 2009 (periodontal treatment vs no treatment); no study in the intensive-treatment vs supra-gingival-scaling comparison reported heart rate.
    Studies not reported
    No studies found

Intensive periodontal treatment (subgingival SRP with or without other periodontal treatment) vs Supra-gingival scaling

Plasma level of IL-6 (pg/mL) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension

Intensive periodontal treatment (subgingival SRP with or without… showed no clear difference in plasma level of IL-6 (pg/mL) compared with supra-gingival scaling; GRADE not reported.

3 findings from 1 review

Intensive periodontal treatment (subgingival SRP with or without other periodontal treatment) vs Supra-gingival scaling

Systolic blood pressure (mmHg), change from baseline · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension

Intensive periodontal treatment (subgingival SRP with or without… probably leads to lower change in systolic blood pressure (SBP, mmHg) compared with supra-gingival scaling (moderate certainty).

3 findings from 1 review

Intensive periodontal treatment (subgingival SRP with or without other periodontal treatment) vs Supra-gingival scaling

Plasma level of hs-CRP (mg/L) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension

Intensive periodontal treatment (subgingival SRP with or without… showed no clear difference in plasma level of hs-CRP (mg/L) compared with supra-gingival scaling; GRADE not reported.

2 findings from 1 review

Intensive periodontal treatment (subgingival SRP with or without other periodontal treatment) vs Supra-gingival scaling

Probing pocket depth · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension

Intensive periodontal treatment (subgingival SRP with or without… led to lower pocket probing depth (PPD) compared with supra-gingival scaling; GRADE not reported.

3 findings from 1 review

Intensive periodontal treatment (subgingival SRP with or without other periodontal treatment) vs Supra-gingival scaling

Endothelial function (endothelial microparticles) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension

Intensive periodontal treatment (subgingival SRP with or without… led to lower endothelial function (endothelial microparticles) compared with supra-gingival scaling; GRADE not reported.

2 findings from 1 review

Intensive periodontal treatment (subgingival SRP with or without other periodontal treatment) vs Supra-gingival scaling

Clinical attachment level (CAL) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension

Intensive periodontal treatment (subgingival SRP with or without… led to lower clinical attachment level (CAL) compared with supra-gingival scaling; GRADE not reported.

3 findings from 1 review

Intensive periodontal treatment (subgingival SRP with or without other periodontal treatment) vs Supra-gingival scaling

Percentage of bleeding on probing (BOP) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension

Intensive periodontal treatment (subgingival SRP with or without… led to lower bleeding on probing (BOP) compared with supra-gingival scaling; GRADE not reported.

2 findings from 1 review

Intensive periodontal treatment (subgingival SRP with or without other periodontal treatment) vs No treatment (no periodontal treatment)

Proportion of participants diagnosed with hypertension at trial completion · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension

The review found no eligible studies for this question.

1 finding from 1 review

Discontinuation by no treatment/placebo of antihypertensives vs continuation

Fatal or nonfatal myocardial infarction · Older adults, 50 years and older

It is very uncertain whether discontinuation by no treatment/placebo of antihypertensives changes myocardial infarction (fatal and nonfatal) compared with continuation (very low certainty).

1 finding from 1 review