Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

116 questions · 120 findings · 11 reviews · Neuromuscular

No studies found 25 · 20.8%GRADE not reported 5 · 4.2%Very low 35 · 29.2%Low 20 · 16.7%Moderate 27 · 22.5%High 8 · 6.7%

Tripterygium polyglycoside vs corticosteroids

Improvement in disability grade Defined as achievement of a specified degree of improvement · patients with Guillain‐Barré syndrome

It is very uncertain whether tripterygium polyglycoside changes improvement in disability grade Defined as achievement of a… compared with corticosteroids (very low certainty).

1 finding from 1 review

Intervention not reported

Presence of PHN 6 months after the onset of acute herpetic rashClinical manifestation · people with acute herpes zoster (within 7 days of onset of rash)

It is very uncertain whether the intervention changes presence of PHN 6 months after the onset of acute herpetic… (very low certainty).

1 finding from 1 review

Intervention not reported

Serious adverse eventsClinical manifestation and laboratory examination · people with acute herpes zoster (within 7 days of onset of rash)

It is very uncertain whether the intervention changes serious adverse eventsClinical manifestation and laboratory… (very low certainty).

1 finding from 1 review

Intervention not reported

Non‐serious adverse eventsClinical manifestation and laboratory examination · people with acute herpes zoster (within 7 days of onset of rash)

The intervention showed no clear difference in non‐serious adverse eventsClinical manifestation and laboratory… (low certainty).

1 finding from 1 review

Brain‐derived neurotrophic factor vs placebo

Death or disability after 12 months · patients with Guillain‐Barré syndrome

It is very uncertain whether brain‐derived neurotrophic factor changes death or disability after 12 months compared with placebo (very low certainty).

1 finding from 1 review

Brain‐derived neurotrophic factor vs placebo

Participants with 1 or more serious adverse events · patients with Guillain‐Barré syndrome

It is very uncertain whether brain‐derived neurotrophic factor changes participants with 1 or more serious adverse events compared with placebo (very low certainty).

1 finding from 1 review

Cerebrospinal fluid filtration vs plasma exchange

Improvement in disability grade Defined as achievement of a specified degree of improvement · patients with Guillain‐Barré syndrome

It is very uncertain whether cerebrospinal fluid filtration changes improvement in disability grade Defined as achievement of a… compared with plasma exchange (very low certainty).

1 finding from 1 review