Findings

What do systematic reviews say?

66 questions · 66 findings · 5 reviews · Wounds

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No studies found 32 · 48.5%GRADE not reported 0 · 0%Very low 27 · 40.9%Low 6 · 9.1%Moderate 1 · 1.5%High 0 · 0%

Polyhexamethylene biguanide (PHMB) vs Normal saline

Number of wounds healed · people with venous leg ulcers

The review found no eligible studies for this question.

1 finding from 1 review

Wound cleansing for treating venous leg ulcers 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Propyl betaine and polihexanide vs Normal saline

Health related quality of life · participants with chronic leg ulcers

The review found no eligible studies for this question.

1 finding from 1 review

Wound cleansing for treating venous leg ulcers 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Propyl betaine and polihexanide vs Normal saline

Adverse events after 4 weeks of · participants with chronic leg ulcers

1 finding from 1 review

Wound cleansing for treating venous leg ulcers 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 38 participants
Very low

Polyhexamethylene biguanide (PHMB) vs Normal saline

Change in ulcer size · people with venous leg ulcers

The review found no eligible studies for this question.

1 finding from 1 review

Wound cleansing for treating venous leg ulcers 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Polyhexamethylene biguanide (PHMB) vs Normal saline

Pain · people with venous leg ulcers

The review found no eligible studies for this question.

1 finding from 1 review

Wound cleansing for treating venous leg ulcers 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Polyhexamethylene biguanide (PHMB) vs Normal saline

Costs · people with venous leg ulcers

The review found no eligible studies for this question.

1 finding from 1 review

Wound cleansing for treating venous leg ulcers 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Polyhexamethylene biguanide (PHMB) vs Normal saline

Health related quality of life · people with venous leg ulcers

The review found no eligible studies for this question.

1 finding from 1 review

Wound cleansing for treating venous leg ulcers 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Polyhexamethylene biguanide (PHMB) vs Normal saline

Adverse events · people with venous leg ulcers

The review found no eligible studies for this question.

1 finding from 1 review

Wound cleansing for treating venous leg ulcers 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

NMA evidence for individual network: proportion with complete healing ‐ interventions vs saline gauze

Hydrogel · people with pressure ulcers

It is very uncertain whether NMA evidence for individual network: proportion with complete… changes hydrogel compared with saline gauze (very low certainty).

1 finding from 1 review

Dressings and topical agents for treating pressure ulcers 2017 · Cochrane Headline outcomes only
RR 1.55 [1.02, 2.36]
Studies not reported
Very low

NMA evidence for individual network: proportion with complete healing ‐ interventions vs saline gauze

Iodine‐containing dressings · people with pressure ulcers

It is very uncertain whether NMA evidence for individual network: proportion with complete… changes iodine‐containing dressings compared with saline gauze (very low certainty).

1 finding from 1 review

Dressings and topical agents for treating pressure ulcers 2017 · Cochrane Headline outcomes only
RR 1.08 [0.58, 2.03]
Studies not reported
Very low

NMA evidence for individual network: proportion with complete healing ‐ interventions vs saline gauze

Phenytoin · people with pressure ulcers

It is very uncertain whether NMA evidence for individual network: proportion with complete… changes phenytoin compared with saline gauze (very low certainty).

1 finding from 1 review

Dressings and topical agents for treating pressure ulcers 2017 · Cochrane Headline outcomes only
RR 1.27 [0.58, 2.8]
Studies not reported
Very low

NMA evidence for individual network: proportion with complete healing ‐ interventions vs saline gauze

Protease‐modulating dressings · people with pressure ulcers

NMA evidence for individual network: proportion with complete… showed no clear difference in protease‐modulating dressings compared with saline gauze (moderate certainty).

1 finding from 1 review

Dressings and topical agents for treating pressure ulcers 2017 · Cochrane Headline outcomes only
RR 1.65 [0.92, 2.94]
Studies not reported
Moderate

NMA evidence for individual network: proportion with complete healing ‐ interventions vs saline gauze

Polyvinylpyrrolidone + zinc oxide · people with pressure ulcers

NMA evidence for individual network: proportion with complete… showed no clear difference in polyvinylpyrrolidone + zinc oxide compared with saline gauze (low certainty).

1 finding from 1 review

Dressings and topical agents for treating pressure ulcers 2017 · Cochrane Headline outcomes only
RR 1.31 [0.37, 4.62]
Studies not reported
Low

NMA evidence for individual network: proportion with complete healing ‐ interventions vs saline gauze

Combination silicone foam dressings · people with pressure ulcers

It is very uncertain whether NMA evidence for individual network: proportion with complete… changes combination silicone foam dressings compared with saline gauze (very low certainty).

1 finding from 1 review

Dressings and topical agents for treating pressure ulcers 2017 · Cochrane Headline outcomes only
RR 1.93 [0.38, 9.98]
Studies not reported
Very low

NMA evidence for individual network: proportion with complete healing ‐ interventions vs saline gauze

Soft polymer dressings · people with pressure ulcers

It is very uncertain whether NMA evidence for individual network: proportion with complete… changes soft polymer dressings compared with saline gauze (very low certainty).

1 finding from 1 review

Dressings and topical agents for treating pressure ulcers 2017 · Cochrane Headline outcomes only
RR 1.35 [0.55, 3.27]
Studies not reported
Very low

NMA evidence for individual network: proportion with complete healing ‐ interventions vs saline gauze

Sugar + egg white · people with pressure ulcers

It is very uncertain whether NMA evidence for individual network: proportion with complete… changes sugar + egg white compared with saline gauze (very low certainty).

1 finding from 1 review

Dressings and topical agents for treating pressure ulcers 2017 · Cochrane Headline outcomes only
RR 0.7 [0.03, 15.62]
Studies not reported
Very low

NMA evidence for individual network: proportion with complete healing ‐ interventions vs saline gauze

Tripeptide copper gel · people with pressure ulcers

It is very uncertain whether NMA evidence for individual network: proportion with complete… changes tripeptide copper gel compared with saline gauze (very low certainty).

1 finding from 1 review

Dressings and topical agents for treating pressure ulcers 2017 · Cochrane Headline outcomes only
RR 3.9 [1.04, 14.63]
Studies not reported
Very low

NMA evidence for individual network: proportion with complete healing ‐ interventions vs saline gauze

Vapour‐permeable dressings · people with pressure ulcers

It is very uncertain whether NMA evidence for individual network: proportion with complete… changes vapour‐permeable dressings compared with saline gauze (very low certainty).

1 finding from 1 review

Dressings and topical agents for treating pressure ulcers 2017 · Cochrane Headline outcomes only
RR 1.45 [0.74, 2.81]
Studies not reported
Very low

NMA evidence for individual network: proportion with complete healing ‐ interventions vs saline gauze

Alginate dressings · people with pressure ulcers

It is very uncertain whether NMA evidence for individual network: proportion with complete… changes alginate dressings compared with saline gauze (very low certainty).

1 finding from 1 review

Dressings and topical agents for treating pressure ulcers 2017 · Cochrane Headline outcomes only
RR 1.09 [0.11, 10.57]
Studies not reported
Very low

NMA evidence for individual network: proportion with complete healing ‐ interventions vs saline gauze

Sequential hydrocolloid alginate dressings · people with pressure ulcers

It is very uncertain whether NMA evidence for individual network: proportion with complete… changes sequential hydrocolloid alginate dressings compared with saline gauze (very low certainty).

1 finding from 1 review

Dressings and topical agents for treating pressure ulcers 2017 · Cochrane Headline outcomes only
RR 0.5 [0.12, 1.98]
Studies not reported
Very low