Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

407 questions · 424 findings · 34 reviews · Headline outcomes only

No studies found 65 · 15.3%GRADE not reported 36 · 8.5%Very low 86 · 20.3%Low 133 · 31.4%Moderate 88 · 20.8%High 16 · 3.8%

Epinephrine vs placebo

Admissions at enrollment or < 24 hours (outpatients only) · patients with acute viral bronchiolitis

Epinephrine probably leads to lower admissions at enrollment or < 24 hours (outpatients only) compared with placebo (moderate certainty).

1 finding from 1 review

Epinephrine vs steroids

Admissions overall up to 7 days (outpatients only) · patients with acute viral bronchiolitis

Epinephrine showed no clear difference in admissions overall up to 7 days (outpatients only) compared with steroid (moderate certainty).

1 finding from 1 review

Epinephrine vs placebo

Admissions overall up to 7 days (outpatients only) · patients with acute viral bronchiolitis

Epinephrine showed no clear difference in admissions overall up to 7 days (outpatients only) compared with placebo (low certainty).

1 finding from 1 review

Epinephrine vs salbutamol/albuterol

Admissions at enrollment or < 24 hours (outpatients only) · patients with acute viral bronchiolitis

Epinephrine showed no clear difference in admissions at enrollment or < 24 hours (outpatients only) compared with salbutamol/albuterol (moderate certainty).

1 finding from 1 review

Epinephrine vs salbutamol/albuterol

Admissions overall up to 7 days (outpatients only) · patients with acute viral bronchiolitis

Epinephrine showed no clear difference in admissions overall up to 7 days (outpatients only) compared with salbutamol/albuterol (moderate certainty).

1 finding from 1 review

Epinephrine and steroid vs placebo

Admissions at enrollment or < 24 hours (outpatients only) · patients with acute viral bronchiolitis

Epinephrine and steroid showed no clear difference in admissions at enrollment or < 24 hours (outpatients only) compared with placebo (low certainty).

1 finding from 1 review

Epinephrine and steroid vs placebo

Admissions overall up to 7 days (outpatients only) · patients with acute viral bronchiolitis

Epinephrine and steroid may leads to lower admissions overall up to 7 days (outpatients only) compared with placebo (low certainty).

1 finding from 1 review

Epinephrine vs steroids

Admissions (outpatients) · patients with acute viral bronchiolitis

Epinephrine showed no clear difference in admissions (outpatients only) compared with steroid (moderate certainty).

1 finding from 1 review

Saline vs carbon dioxide

Adverse events and complications · women undergoing outpatient hysteroscopy

Saline probably leads to lower adverse events and complications compared with carbon dioxide (moderate certainty).

1 finding from 1 review