Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

191 questions · 196 findings · 20 reviews · Cystic Fibrosis and Genetic Disorders

No studies found 65 · 33.2%GRADE not reported 9 · 4.6%Very low 26 · 13.3%Low 46 · 23.5%Moderate 36 · 18.4%High 14 · 7.1%

Summary of findings: oral β‐carotene vs placebo

FEV1 % predicted: absolute change from baseline · adults and children with cystic fibrosis

The review found no eligible studies for this question.

2 findings from 1 review

Oral ciprofloxacin and inhaled colistin vs inhaled tobramycin

Eradication of P aeruginosa from the respiratory tract: proportion with positive respiratory culture for P aeruginosa · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen

It is very uncertain whether oral ciprofloxacin and inhaled colistin changes eradication of P aeruginosa from the respiratory tract: proportion… compared with inhaled tobramycin (TNS) (very low certainty).

1 finding from 1 review