Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

166 questions · 178 findings · 15 reviews

No studies found 52 · 29.2%GRADE not reported 1 · 0.6%Very low 44 · 24.7%Low 56 · 31.5%Moderate 24 · 13.5%High 1 · 0.6%

Dose comparison: oestrogen 100 µg patch vs 200 µg patch plus progestogen

Adverse events ‐ specific side effects attributed to oestrogen over 8 months' · women with PMS

It is very uncertain whether dose comparison: oestrogen 100 µg patch changes adverse events ‐ specific side effects attributed to oestrogen over… compared with 200 µg patch plus progestogen (very low certainty).

1 finding from 1 review

Antioestrogen plus medical adjunct vs antioestrogen

Clinical pregnancy · ovulation induction in polycystic ovarian syndrome

Antioestrogen plus medical adjunct showed no clear difference in clomiphene citrate plus bromocriptine versus clomiphene citrate ‐… compared with antioestrogen alone (low certainty).

1 finding from 1 review

Transdermal oestrogens vs oral oestrogens

Clinical pregnancy rate · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes

Transdermal oestrogens showed no clear difference in clinical pregnancy rate compared with oral oestrogens (low certainty).

1 finding from 1 review