Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

72 questions · 72 findings · 9 reviews

No studies found 13 · 18.1%GRADE not reported 0 · 0%Very low 37 · 51.4%Low 15 · 20.8%Moderate 3 · 4.2%High 4 · 5.6%

NSAIDs vs placebo

Substantial benefit: At least 50% reduction in pain, or PGIC much improved · adults with fibromyalgia

It is very uncertain whether NSAID changes substantial pain relief: at least 50% reduction in pain, or PGIC… compared with placebo (very low certainty).

1 finding from 1 review

NSAIDs vs placebo

Moderate benefit: At least 30% reduction in pain, or PGIC much or very much improved · adults with fibromyalgia

It is very uncertain whether NSAID changes moderate pain relief: at least 30% reduction in pain, or PGIC much… compared with placebo (very low certainty).

1 finding from 1 review