Adverse events (hot flushes) · women with uterine fibroids
GnRHa treatment may leads to higher adverse events (hot flushes) compared with other medical therapies before any surgery (low certainty).
1 finding from 1 review
Bleeding · heavy menstrual bleeding
1 finding from 1 review
Satisfaction · heavy menstrual bleeding
It is very uncertain whether LNG‐IUS changes satisfaction compared with any other medical treatment (very low certainty).
1 finding from 1 review
Quality of life · heavy menstrual bleeding
1 finding from 1 review
Adverse events · heavy menstrual bleeding
LNG‐IUS probably leads to lower adverse events compared with any other medical treatment (moderate certainty).
1 finding from 1 review
Treatment withdrawal for any reason Duration of treatment (range): 12 (3 months) to 36 weeks · heavy menstrual bleeding
LNG‐IUS probably leads to lower withdrawal from treatment for any reason compared with any other medical treatment (moderate certainty).
1 finding from 1 review
Treatment failure · heavy menstrual bleeding
LNG‐IUS probably leads to lower treatment failure compared with any other medical treatment (moderate certainty).
1 finding from 1 review
Costs · heavy menstrual bleeding
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Menstrual blood loss: mean loss · women with heavy menstrual bleeding
1 finding from 1 review
Quality of life · women with heavy menstrual bleeding
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse effects: headache · women with heavy menstrual bleeding
Progestogen therapy long cycle (3 to 4 weeks) showed no clear difference in adverse effect Headache compared with other medical therapy (low certainty).
1 finding from 1 review
Adverse effect Breakthrough bleeding/spotting · women with heavy menstrual bleeding
Progestogen therapy long cycle (3 to 4 weeks) may leads to lower adverse effect Breakthrough bleeding/spotting compared with other medical therapy (low certainty).
1 finding from 1 review
Satisfaction · women with heavy menstrual bleeding
It is very uncertain whether progestogen therapy (luteal phase only) changes satisfaction compared with other medical therapy (very low certainty).
1 finding from 1 review
Days of bleeding · women with heavy menstrual bleeding
1 finding from 1 review
Physical functioning component of health‐related quality of life, measured using various scales · women with heavy menstrual bleeding
1 finding from 1 review
Total adverse effects · women with heavy menstrual bleeding
It is very uncertain whether progestogen therapy (luteal phase only) changes total adverse effects compared with other medical therapy (very low certainty).
1 finding from 1 review
Menstrual blood loss PBAC score · women with heavy menstrual bleeding
2 findings from 1 review
Satisfaction · women with heavy menstrual bleeding
Progestogen therapy long cycle (3 to 4 weeks) may leads to lower satisfaction compared with other medical therapy (low certainty).
1 finding from 1 review
Days of bleeding · women with heavy menstrual bleeding
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Self‐reported pain (dysmenorrhoea) at the end of treatment (continuous data): dysmenorrhoea at 6 months' · women with endometriosis
2 findings from 1 review