Femur fracture · European GWAS participants
The MVMR MR-Egger interval included the null.
1 finding from 1 review
OR 1.024 [0.960, 1.093]
489106 participants
GRADE not reported
Postmenopausal osteoporosis with pathological fracture · European GWAS participants
The MVMR MR-Egger interval included the null.
1 finding from 1 review
OR 1.012 [0.858, 1.193]
281786 participants
GRADE not reported
Osteoporosis with pathological fracture · European GWAS participants
The MVMR MR-Egger interval included the null.
1 finding from 1 review
OR 1.002 [0.867, 1.158]
376746 participants
GRADE not reported
Bone mineral density in forearm · European-ancestry adults
Genetically predicted periodontitis had no causal effect on forearm BMD.
1 finding from 1 review
Osteoporosis · European GWAS participants
The SVMR Weighted Median interval excluded the null.
3 findings from 1 review
OR 1.260 [1.017, 1.560]
483725 participants
GRADE not reported
OR 1.162 [0.998, 1.353]
483725 participants
GRADE not reported
OR 1.329 [0.991, 1.782]
483725 participants
GRADE not reported
Lumbar spine bone mineral density (BMD) · European GWAS participants
The SVMR IVW interval excluded zero.
1 finding from 1 review
Forearm fracture · European-ancestry adults
Genetically predicted periodontitis had no causal effect on fracture of forearm (multivariable MR, OR 0.995).
2 findings from 1 review
Femur fracture · European GWAS participants
The SVMR Weighted Median interval included the null.
3 findings from 1 review
OR 1.055 [0.979, 1.136]
489106 participants
GRADE not reported
OR 1.044 [0.983, 1.109]
489106 participants
GRADE not reported
OR 1.063 [0.991, 1.140]
489106 participants
GRADE not reported
Postmenopausal osteoporosis with pathological fracture · European GWAS participants
The SVMR Weighted Median interval included the null.
3 findings from 1 review
OR 0.979 [0.826, 1.159]
281786 participants
GRADE not reported
OR 1.014 [0.872, 1.179]
281786 participants
GRADE not reported
OR 0.934 [0.786, 1.111]
281786 participants
GRADE not reported
Postmenopausal osteoporosis with pathological fracture · Postmenopausal women (European ancestry)
Genetically predicted periodontitis had no causal effect on postmenopausal osteoporosis with pathological fracture (single-variable MR, OR 1.014).
2 findings from 1 review
Osteoporosis · European GWAS participants
The MVMR MR-Egger interval included the null.
1 finding from 1 review
OR 1.005 [0.940, 1.074]
483725 participants
GRADE not reported
Femur fracture · European-ancestry adults
Genetically predicted dental caries (DMFS) had no significant causal effect on fracture of femur (multivariable MR, OR 1.069).
2 findings from 1 review
Lumbar spine and pelvis fracture · European GWAS participants
The MVMR MR-Egger interval included the null.
1 finding from 1 review
OR 1.034 [0.769, 1.390]
490700 participants
GRADE not reported
Postmenopausal osteoporosis with pathological fracture · European GWAS participants
The MVMR MR-Egger interval included the null.
1 finding from 1 review
OR 1.281 [0.640, 2.565]
281786 participants
GRADE not reported
Lumbar spine bone mineral density (BMD) · European GWAS participants
The MVMR IVW interval excluded zero.
1 finding from 1 review
Forearm fracture · European GWAS participants
The SVMR Weighted Median interval included the null.
3 findings from 1 review
OR 0.914 [0.799, 1.046]
490889 participants
GRADE not reported
OR 0.883 [0.738, 1.057]
490889 participants
GRADE not reported
OR 0.920 [0.836, 1.011]
490889 participants
GRADE not reported
Osteoporosis with pathological fracture · European GWAS participants
The MVMR MR-Egger interval included the null.
1 finding from 1 review
OR 1.011 [0.876, 1.167]
376746 participants
GRADE not reported
Spontaneous space closure · Children and adolescents after extraction of a mandibular permanent first molar (before eruption of the second molar)
In the mandible, mean patient age was not significantly associated with space closure odds (OR 0.59 per year; not GRADE-rated).
1 finding from 1 review