Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

77 questions · 79 findings · 25 reviews · Airways

No studies found 0 · 0%GRADE not reported 3 · 3.8%Very low 8 · 10.1%Low 37 · 46.8%Moderate 20 · 25.3%High 11 · 13.9%

Intervention not reported

Asthma control (ACQ) Scale 0 to 6; lower is better12 months · adults or children with asthma
1 finding from 1 review

Intervention not reported

Health‐related quality of life (disease‐specific) Scale from 0 to 100; lower score indicates better HRQoL. SGRQ total score consists of weighted scores from 3 domains · individuals with stable bronchiectasis
1 finding from 1 review

Intervention not reported

Respiratory symptoms (symptoms) Breathlessness, Cough and Sputum Scale Scale from 0 to 12. Lower score indicates fewer symptoms · individuals with stable bronchiectasis

The intervention showed no clear difference in respiratory symptoms (symptoms) Breathlessness, Cough and Sputum… (low certainty).

1 finding from 1 review

Intervention not reported

TDI Total scores range from ‐ 9 to +9. The lower the score, the greater the deterioration in severity of dyspnoea, MCID ≥ 1 · 18 to 80 years of age with bronchiectasis

The intervention may leads to higher TDI Total scores range from ‐ 9 to +9. The lower the score, the… (low certainty).

1 finding from 1 review

Long‐acting beta2‐agonists vs placebo

Quality of life St George's Respiratory Questionnaire (SGRQ) score · patients with chronic obstructive pulmonary disease

Long‐acting beta2‐agonists showed no clear difference in quality of life1 St George's Respiratory Questionnaire (SGRQ); lower… compared with placebo (moderate certainty).

1 finding from 1 review