Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

289 questions · 326 findings · 19 reviews · Drugs and Alcohol

No studies found 13 · 4%GRADE not reported 33 · 10.1%Very low 108 · 33.1%Low 109 · 33.4%Moderate 52 · 16%High 11 · 3.4%

Integrated parenting and substance use‐focused component psychosocial interventions vs treatment

Frequency of drug use 12 months · Parents who use substances
2 findings from 1 review

Parenting‐focused psychosocial interventions WITHOUT substance use‐focused component vs treatment

Frequency of drug use 12 months · Parents who use substances
2 findings from 1 review

Interpersonal Psychotherapy for Depression (IPT‐D) vs Other Psychological Interventions

Substance use ‐ relapse · co‐occurring depression and substance use disorders

It is very uncertain whether interpersonal Psychotherapy for Depression (IPT‐D) changes substance use ‐ relapse compared with other Psychological Interventions (very low certainty).

1 finding from 1 review

Interpersonal Psychotherapy for Depression (IPT‐D) vs Other Psychological Interventions

Retention in treatment · co‐occurring depression and substance use disorders

It is very uncertain whether interpersonal Psychotherapy for Depression (IPT‐D) changes treatment retention compared with other Psychological Interventions (very low certainty).

1 finding from 1 review

Interpersonal Psychotherapy for Depression (IPT‐D) vs Other Psychological Interventions

Depression score · co‐occurring depression and substance use disorders
2 findings from 1 review

Alcoholics Anonymous (AA)/Twelve‐Step Facilitation (TSF) (manualized) vs other clinical interventions

Abstinence · adults (> 18 years) with alcohol use disorder, alcohol abuse, or alcohol dependence

Alcoholics Anonymous (AA)/Twelve‐Step Facilitation (TSF) (manualized) leads to higher abstinence compared with other clinical interventions (high certainty).

2 findings from 1 review

Alcoholics Anonymous (AA)/Twelve‐Step Facilitation (TSF) (manualized) vs other clinical interventions

Drinking Intensity · adults (> 18 years) with alcohol use disorder, alcohol abuse, or alcohol dependence
2 findings from 1 review

Alcoholics Anonymous (AA)/Twelve‐Step Facilitation (TSF) (manualized) vs other clinical interventions

Alcohol‐related consequences · adults (> 18 years) with alcohol use disorder, alcohol abuse, or alcohol dependence
2 findings from 1 review

Alcoholics Anonymous (AA)/Twelve‐Step Facilitation (TSF) (manualized) vs other clinical interventions

Addiction Severity Index alcohol score · adults (> 18 years) with alcohol use disorder, alcohol abuse, or alcohol dependence
2 findings from 1 review

Alcoholics Anonymous (AA)/Twelve‐Step Facilitation (TSF) (non‐manualized) vs other clinical interventions

Abstinence · adults (> 18 years) with alcohol use disorder, alcohol abuse, or alcohol dependence

Alcoholics Anonymous (AA)/Twelve‐Step Facilitation (TSF)… showed no clear difference in abstinence compared with other clinical interventions (low certainty).

1 finding from 1 review