Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

82 questions · 82 findings · 4 reviews

No studies found 12 · 14.6%GRADE not reported 0 · 0%Very low 25 · 30.5%Low 29 · 35.4%Moderate 16 · 19.5%High 0 · 0%

Calcineurin inhibitors ± steroids vs placebo/no treatment/supportive treatment/steroids

Adverse events ‐ infection at 36 months · primary membranous nephropathy in adults with nephrotic syndrome

It is very uncertain whether calcineurin inhibitors ± steroids changes adverse events ‐ infection at 36 months compared with placebo/no treatment/supportive treatment/steroids (very low certainty).

1 finding from 1 review

Calcineurin inhibitors ± steroids vs placebo/no treatment/supportive treatment/steroids

Adverse events ‐ malignancy at 36 months · primary membranous nephropathy in adults with nephrotic syndrome

It is very uncertain whether calcineurin inhibitors ± steroids changes adverse events ‐ malignancy at 36 months compared with placebo/no treatment/supportive treatment/steroids (very low certainty).

1 finding from 1 review