What do systematic reviews say?

Summary of findings table ‐ Adhesiolysis vs no surgery or diagnostic laparoscopy

The review found no eligible studies for this question.

• Surgical interventions for the management of chronic pelvic pain in women 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Oral progestogen (dienogest, desogestrel) vs goserelin acetate

• Progestogens or progestogen‐releasing intrauterine systems for uterine fibroids (other than preoperative medical… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 14 participants
  Very low

Second‐generation endometrial ablation vs first‐generation endometrial ablation

It is very uncertain whether overall analyses: second‐generation endometrial ablation changes proportion given local anaesthesia (%) compared with first‐generation endometrial ablation (very low certainty).

• Endometrial resection and ablation techniques for heavy menstrual bleeding 2019 · Cochrane Headline outcomes only
  RR 2.78 [1.76, 4.4]
  6 studies · 1434 participants
  Very low

GnRHa treatment vs other medical therapies before any surgery

GnRHa treatment may leads to higher adverse events (hot flushes) compared with other medical therapies before any surgery (low certainty).

• Preoperative medical therapy before surgery for uterine fibroids 2017 · Cochrane Headline outcomes only
  OR 12.3 [4.04, 37.48]
  5 studies · 453 participants
  Low

LOD vs other surgical interventions

It is very uncertain whether LOD changes harms: Adhesions at 6 months ‐ LOD vs THL N of participants: 246 (1… compared with other surgical interventions (very low certainty).

• Ovarian surgery for symptom relief in women with polycystic ovary syndrome 2017 · Cochrane Headline outcomes only
  OR 0.1 [0.05, 0.18]
  Studies not reported
  Very low

LOD vs LOD variable energy

It is very uncertain whether LOD changes harms: Adhesions at 6 months № of participants: 64 (1 study) compared with LOD variable energy (very low certainty).

• Ovarian surgery for symptom relief in women with polycystic ovary syndrome 2017 · Cochrane Headline outcomes only
  OR 0.96 [0.32, 2.88]
  Studies not reported
  Very low

Gestrinone vs danazol

It is very uncertain whether gestrinone changes side effects: hot flushes compared with danazol (very low certainty).

• Progesterone receptor modulators for endometriosis 2017 · Cochrane Headline outcomes only
  OR 0.79 [0.5, 1.26]
  2 studies · 302 participants
  Very low

Gestrinone vs leuprolin

Gestrinone may leads to lower side effects: hot flushes compared with leuprolin (low certainty).

• Progesterone receptor modulators for endometriosis 2017 · Cochrane Headline outcomes only
  OR 0.2 [0.06, 0.63]
  1 study · 55 participants
  Low

Mifepristone (all doses) vs placebo

Mifepristone leads to higher side effects: hot flushes compared with placebo (high certainty).

• Progesterone receptor modulators for endometriosis 2017 · Cochrane Headline outcomes only
  OR 28.79 [3.93, 210.73]
  1 study · 360 participants
  High

Chinese herbal medicines vs placebo

• Chinese herbal medicine for menopausal symptoms 2016 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 199 participants
  Moderate

Chinese herbal medicines vs placebo

• Chinese herbal medicine for menopausal symptoms 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 108 participants
  Moderate

Chinese herbal medicines vs placebo

• Chinese herbal medicine for menopausal symptoms 2016 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 263 participants
  Low

Chinese herbal medicines vs placebo

• Chinese herbal medicine for menopausal symptoms 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 84 participants
  Very low

GnRH‐a + raloxifene vs GnRH‐a ± placebo

• Add‐back therapy with GnRH analogues for uterine fibroids 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 91 participants
  Low

Exercise vs control

• Exercise for vasomotor menopausal symptoms 2014 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 454 participants
  Low

Exercise vs yoga

• Exercise for vasomotor menopausal symptoms 2014 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 279 participants
  Low

Intervention not reported

• Relaxation for perimenopausal and postmenopausal symptoms 2014 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 72 participants
  Very low

Intervention not reported

• Relaxation for perimenopausal and postmenopausal symptoms 2014 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 72 participants
  Very low

Oral progestagens vs other treatment

Oral progestagens may leads to lower side effects ‐ hot flushes compared with other treatment (low certainty).

• Progestagens and anti‐progestagens for pain associated with endometriosis 2012 · Cochrane Headline outcomes only
  OR 0.49 [0.31, 0.76]
  3 studies · 613 participants
  Low

Anti‐progestagen vs other treatment

It is very uncertain whether anti‐progestagen changes side effects ‐ hot flushes compared with other treatment (very low certainty).

• Progestagens and anti‐progestagens for pain associated with endometriosis 2012 · Cochrane Headline outcomes only
  OR 0.65 [0.42, 0.99]
  3 studies · 357 participants
  Very low