Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,355 questions · 2,459 findings · 279 reviews

No studies found 556 · 22.6%GRADE not reported 490 · 19.9%Very low 593 · 24.1%Low 479 · 19.5%Moderate 243 · 9.9%High 98 · 4%

No additional acid etching (self-etch adhesive alone) after Er,Cr:YSGG preparation vs Prior acid etching before self-etch adhesive after Er,Cr:YSGG preparation

Incidence of microleakage · Er,Cr:YSGG laser-prepared cavities restored with self-etch adhesive systems (in vitro)

At the dentin margin, prior acid etching with self-etch adhesives significantly reduced microleakage (RR 2.44, 95% CI 1.38-4.34; ungraded).

3 findings from 1 review

No additional acid etching (etch-and-rinse adhesive alone) after Er,Cr:YSGG preparation vs Prior acid etching before etch-and-rinse adhesive after Er,Cr:YSGG preparation

Incidence of microleakage · Er,Cr:YSGG laser-prepared cavities restored with etch-and-rinse adhesive systems (in vitro)

Prior acid etching with etch-and-rinse adhesives did not significantly change microleakage after Er,Cr:YSGG preparation (RR 1.18, 95% CI 0.63-2.22; ungraded).

1 finding from 1 review

General anaesthesia vs non‐general anaesthesia

Functional outcomes · acute ischaemic stroke endovascular treatment (long‐term)
3 findings from 1 review

General anaesthesia vs non‐general anaesthesia

Neurological impairment · acute ischaemic stroke endovascular treatment (long‐term)

The review found no eligible studies for this question.

2 findings from 1 review

General anaesthesia vs non‐general anaesthesia

Stroke‐related mortality · acute ischaemic stroke endovascular treatment (long‐term)

General anaesthesia showed no clear difference in stroke‐related mortality compared with non‐general anaesthesia (low certainty).

2 findings from 1 review

General anaesthesia vs non‐general anaesthesia

Intracranial haemorrhage · acute ischaemic stroke endovascular treatment (long‐term)

The review found no eligible studies for this question.

2 findings from 1 review

General anaesthesia vs non‐general anaesthesia

Time to revascularisation · acute ischaemic stroke endovascular treatment (long‐term)

The review found no eligible studies for this question.

2 findings from 1 review

General anaesthesia vs non‐general anaesthesia

Target artery revascularisation (dichotomous; mTICI 2b–3) · acute ischaemic stroke endovascular treatment (long‐term)

General anaesthesia probably leads to higher target artery revascularisation (dichotomous; mTICI 2b–3) compared with non‐general anaesthesia (moderate certainty).

1 finding from 1 review

ACP light-cure adhesive vs Conventional/control orthodontic adhesive (e.g., Transbond XT) or negative control

Enamel demineralization (DIAGNOdent score) · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)

ACP adhesive had lower demineralization scores at 1 month, with certainty not graded.

2 findings from 1 review