50% responder rate · people with focal or generalized seizures
Clobazam showed no clear difference in 50% responder rate compared with carbamazepine (low certainty).
1 finding from 1 review
Adverse effects requiring withdrawal/discontinuation of study medication · people with focal or generalized seizures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Time on allocated treatment (retention time) · drug‐naïve people with focal or generalized seizures with solitary cysticercus granuloma
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Retention [ · drug‐naïve people with focal or generalized seizures with solitary cysticercus granuloma
Clobazam may leads to higher retention at 6 months (measured by the number of treatment failures… compared with phenytoin (low certainty).
1 finding from 1 review
Intervention not reported
Time to treatment withdrawal ‐ all participants Range of · adults and children with newly diagnosed partial onset or generalised onset seizures
The intervention may leads to higher time to treatment withdrawal ‐ all participants Range of (low certainty).
1 finding from 1 review
Intervention not reported
Time to first seizure ‐ all participants Range of · adults and children with newly diagnosed partial onset or generalised onset seizures
The intervention showed no clear difference in time to first seizure ‐ all participants Range of (moderate certainty).
1 finding from 1 review
Intervention not reported
Time to first seizure ‐ stratified by epilepsy type ‐ Partial onset Range of · adults and children with newly diagnosed partial onset or generalised onset seizures
The intervention showed no clear difference in time to first seizure ‐ stratified by epilepsy type ‐ Partial onset… (moderate certainty).
1 finding from 1 review
Intervention not reported
Time to treatment withdrawal ‐ stratified by seizure type ‐ Partial onset Range of · adults and children with newly diagnosed partial onset or generalised onset seizures
The intervention may leads to higher time to treatment withdrawal ‐ stratified by seizure type ‐ Partial… (low certainty).
1 finding from 1 review
Intervention not reported
Time to 12‐month remission ‐ all participants Range of · adults and children with newly diagnosed partial onset or generalised onset seizures
The intervention showed no clear difference in time to 12‐month remission ‐ all participants Range of (moderate certainty).
1 finding from 1 review
Intervention not reported
Time to 12‐month remission ‐ stratified by seizure type ‐ Partial Onset Range of · adults and children with newly diagnosed partial onset or generalised onset seizures
The intervention showed no clear difference in time to 12‐month remission ‐ stratified by seizure type ‐ Partial… (moderate certainty).
1 finding from 1 review
Intervention not reported
Time to 6‐month remission ‐ all participants Range of · adults and children with newly diagnosed partial onset or generalised onset seizures
The intervention showed no clear difference in time to 6‐month remission ‐ all participants Range of (moderate certainty).
1 finding from 1 review
Intervention not reported
Time to 6‐month remission ‐ stratified by seizure type ‐ Partial onset Range of · adults and children with newly diagnosed partial onset or generalised onset seizures
The intervention showed no clear difference in time to 6‐month remission ‐ stratified by seizure type ‐ Partial… (moderate certainty).
1 finding from 1 review
Intervention not reported
Comparison (reference treatment) · adults and children with generalised seizures*
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Sodium valproate · adults and children with generalised seizures*
1 finding from 1 review
Intervention not reported
Any reason · adults and children with generalised tonic‐clonic seizures with or without other seizure types
1 finding from 1 review
Intervention not reported
Adverse events · adults and children with generalised tonic‐clonic seizures with or without other seizure types
1 finding from 1 review
Intervention not reported
Lack of efficacy · adults and children with generalised tonic‐clonic seizures with or without other seizure types
1 finding from 1 review
Time to treatment failure (any reason related to treatment) All participants Range of · adults and children with newly onset partial or generalised epilepsy
Carbamazepine showed no clear difference in time to treatment failure (any reason related to treatment)All… compared with phenytoin (time to treatment failure) (moderate certainty).
1 finding from 1 review
Time to treatment failure (any reason related to treatment) Subgroup: focal onset seizures Range of · adults and children with newly onset partial or generalised epilepsy
Carbamazepine showed no clear difference in time to treatment failure (any reason related to treatment)… compared with phenytoin (time to treatment failure) (moderate certainty).
1 finding from 1 review
Time to first seizure (post‐randomisation) All participants Range of · adults and children with newly onset partial or generalised epilepsy
Carbamazepine showed no clear difference in time to first seizure after randomisationAll participants Range of compared with phenytoin (secondary outcomes) (moderate certainty).
1 finding from 1 review