What do systematic reviews say?

Summary of findings table ‐ Prothrombin complex concentrates vs fresh frozen plasma

It is very uncertain whether summary of findings table ‐ Prothrombin complex concentrates changes death or dependence (mRS 4–6) compared with fresh frozen plasma (very low certainty).

• Haemostatic therapies for stroke due to acute, spontaneous intracerebral haemorrhage 2023 · Cochrane Headline outcomes only
  RR 1.21 [0.76, 1.9]
  1 study · 37 participants
  Very low

Summary of findings table ‐ Prothrombin complex concentrates vs fresh frozen plasma

It is very uncertain whether summary of findings table ‐ Prothrombin complex concentrates changes intracerebral haemorrhage expansion by 24 hours compared with fresh frozen plasma (very low certainty).

• Haemostatic therapies for stroke due to acute, spontaneous intracerebral haemorrhage 2023 · Cochrane Headline outcomes only
  RR 0.54 [0.23, 1.22]
  1 study · 36 participants
  Very low

Summary of findings table ‐ Prothrombin complex concentrates vs fresh frozen plasma

It is very uncertain whether summary of findings table ‐ Prothrombin complex concentrates changes all serious adverse events compared with fresh frozen plasma (very low certainty).

• Haemostatic therapies for stroke due to acute, spontaneous intracerebral haemorrhage 2023 · Cochrane Headline outcomes only
  RR 0.27 [0.02, 3.74]
  1 study · 5 participants
  Very low

Summary of findings table ‐ Prothrombin complex concentrates vs fresh frozen plasma

It is very uncertain whether summary of findings table ‐ Prothrombin complex concentrates changes death from any cause compared with fresh frozen plasma (very low certainty).

• Haemostatic therapies for stroke due to acute, spontaneous intracerebral haemorrhage 2023 · Cochrane Headline outcomes only
  RR 0.49 [0.16, 1.56]
  2 studies · 42 participants
  Very low

Summary of findings table ‐ Prothrombin complex concentrates vs fresh frozen plasma

The review found no eligible studies for this question.

• Haemostatic therapies for stroke due to acute, spontaneous intracerebral haemorrhage 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings table ‐ Prothrombin complex concentrates vs fresh frozen plasma

The review found no eligible studies for this question.

• Haemostatic therapies for stroke due to acute, spontaneous intracerebral haemorrhage 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings table ‐ Prothrombin complex concentrates vs fresh frozen plasma

The review found no eligible studies for this question.

• Haemostatic therapies for stroke due to acute, spontaneous intracerebral haemorrhage 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Swim‐up technique vs gradient technique

The review found no eligible studies for this question.

• Semen preparation techniques for intrauterine insemination 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Swim‐up technique vs wash and centrifugation

• Semen preparation techniques for intrauterine insemination 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 20 participants
  Very low

Gradient technique vs wash and centrifugation

The review found no eligible studies for this question.

• Semen preparation techniques for intrauterine insemination 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Gradient technique vs wash and centrifugation

It is very uncertain whether gradient technique changes clinical pregnancy rate per couple compared with wash and centrifugation (very low certainty).

• Semen preparation techniques for intrauterine insemination 2019 · Cochrane Headline outcomes only
  OR 1.78 [0.58, 5.46]
  2 studies · 94 participants
  Very low

Gradient technique vs wash and centrifugation

The review found no eligible studies for this question.

• Semen preparation techniques for intrauterine insemination 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Gradient technique vs wash and centrifugation

It is very uncertain whether gradient technique changes multiple pregnancy rate per couple compared with wash and centrifugation (very low certainty).

• Semen preparation techniques for intrauterine insemination 2019 · Cochrane Headline outcomes only
  OR 0.33 [0.01, 8.83]
  1 study · 31 participants
  Very low

Gradient technique vs wash and centrifugation

It is very uncertain whether gradient technique changes miscarriage rate per couple compared with wash and centrifugation (very low certainty).

• Semen preparation techniques for intrauterine insemination 2019 · Cochrane Headline outcomes only
  OR 6.11 [0.27, 138.45]
  1 study · 31 participants
  Very low

Swim‐up technique vs gradient technique

It is very uncertain whether swim‐up technique changes clinical pregnancy rate per couple compared with gradient technique (very low certainty).

• Semen preparation techniques for intrauterine insemination 2019 · Cochrane Headline outcomes only
  OR 0.83 [0.51, 1.35]
  4 studies · 370 participants
  Very low

Swim‐up technique vs gradient technique

It is very uncertain whether swim‐up technique changes ongoing pregnancy rate per couple compared with gradient technique (very low certainty).

• Semen preparation techniques for intrauterine insemination 2019 · Cochrane Headline outcomes only
  OR 0.39 [0.19, 0.82]
  1 study · 223 participants
  Very low

Swim‐up technique vs gradient technique

• Semen preparation techniques for intrauterine insemination 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 25 participants
  Very low

Swim‐up technique vs gradient technique

It is very uncertain whether swim‐up technique changes miscarriage rate per couple compared with gradient technique (very low certainty).

• Semen preparation techniques for intrauterine insemination 2019 · Cochrane Headline outcomes only
  OR 0.85 [0.28, 2.59]
  3 studies · 330 participants
  Very low

Swim‐up technique vs wash and centrifugation

The review found no eligible studies for this question.

• Semen preparation techniques for intrauterine insemination 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Swim‐up technique vs wash and centrifugation

It is very uncertain whether swim‐up technique changes clinical pregnancy rate per couple compared with wash and centrifugation (very low certainty).

• Semen preparation techniques for intrauterine insemination 2019 · Cochrane Headline outcomes only
  OR 0.41 [0.15, 1.13]
  2 studies · 78 participants
  Very low