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What do systematic reviews say?

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Evidence found and GRADE certainty

51 questions · 57 findings · 10 reviews

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No studies found 32 · 56.1%GRADE not reported 2 · 3.5%Very low 12 · 21.1%Low 1 · 1.8%Moderate 6 · 10.5%High 4 · 7%

Intervention not reported

Substantial benefit: at least 50% reduction in pain, or PGIC much improved · Adults with chronic neuropathic pain

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Lack of efficacy withdrawal in randomised double‐blind phase · Adults with chronic neuropathic pain
1 finding from 1 review

Intervention not reported

Adverse event withdrawal in randomised double‐blind phase · Adults with chronic neuropathic pain
1 finding from 1 review

Intervention not reported

Serious adverse events · Adults with chronic neuropathic pain
1 finding from 1 review

Intervention not reported

Deaths · Adults with chronic neuropathic pain
1 finding from 1 review

Intervention not reported

Pain reduction (mean VAS) Pain assessed before analgesia (0 min) and at 5, 10, 20 and 30 min after analgesia · children (aged < 18 years) with acute severe pain
1 finding from 1 review