Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

259 questions · 272 findings · 23 reviews · Headline outcomes only

No studies found 68 · 25%GRADE not reported 10 · 3.7%Very low 79 · 29%Low 57 · 21%Moderate 42 · 15.4%High 16 · 5.9%

Antibiotic prophylaxis vs placebo

SSSI · prevention of postoperative wound infection in adults undergoing open elective inguinal or femoral hernioplasty hernia repair

Antibiotic prophylaxis probably leads to lower SSSI compared with placebo (moderate certainty).

1 finding from 1 review

Antibiotic prophylaxis vs placebo

SSSI ‐ low infection risk environment · prevention of postoperative wound infection in adults undergoing open elective inguinal or femoral hernioplasty hernia repair

Antibiotic prophylaxis showed no clear difference in SSSI ‐ low infection risk environment compared with placebo (moderate certainty).

1 finding from 1 review

Antibiotic prophylaxis vs placebo

SSSI ‐ high infection risk environment · prevention of postoperative wound infection in adults undergoing open elective inguinal or femoral hernioplasty hernia repair

It is very uncertain whether antibiotic prophylaxis changes SSSI ‐ high infection risk environment compared with placebo (very low certainty).

1 finding from 1 review

Transverse groin incision vs vertical groin incision

Lymphatic complications: Lymphatic leak (28 days) Lymphatic collection (28 days) · patients undergoing surgery with femoral artery approach

It is very uncertain whether transverse groin incision changes lymphatic complications: Lymphatic leak (28 days) Lymphatic… compared with vertical groin incision (very low certainty).

1 finding from 1 review

Mesh vs non‐mesh repair

Surgical complications ‐ neurovascular or visceral injury · adults undergoing inguinal and femoral hernia repair

Mesh leads to lower surgical complications ‐ neurovascular or visceral injury compared with non‐mesh repair (high certainty).

1 finding from 1 review