Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

76 questions · 86 findings · 14 reviews · Common Mental Disorders

No studies found 11 · 12.8%GRADE not reported 8 · 9.3%Very low 34 · 39.5%Low 26 · 30.2%Moderate 6 · 7%High 1 · 1.2%

Adjunctive couple or family therapy vs structured or non‐specific individual therapy alone

Dropout · post‐traumatic stress disorder (PTSD)

Adjunctive couple or family therapy showed no clear difference in treatment dropout (treatment acceptability) compared with structured or non‐specific individual therapy alone (low certainty).

1 finding from 1 review

Music therapy plus treatment as usual (TAU) vs TAU

Any adverse events Up to 3 months · patients with depression

Music therapy plus treatment as usual (TAU) showed no clear difference in any adverse events Up to 3 months compared with TAU (low certainty).

1 finding from 1 review

Music therapy plus treatment as usual (TAU) vs TAU

Behaviour: Leaving the study early (short‐term) · patients with depression

Music therapy plus treatment as usual (TAU) showed no clear difference in leaving the study early Up to 3 months compared with TAU (moderate certainty).

1 finding from 1 review

Non‐trauma‐focused psychological intervention for PTSD and SUD or PTSD only vs control intervention

Drug or alcohol use, or both following treatment completion ‐ Group‐based intervention As assessed by the ASI, TLFB or CIDI. High scores indicate greater symptom severity · Individuals with post‐traumatic stress disorder and comorbid substance use disorder
1 finding from 1 review

Non‐trauma‐focused psychological intervention for PTSD and SUD or PTSD only vs control intervention

Treatment completers ‐ Group‐based intervention · Individuals with post‐traumatic stress disorder and comorbid substance use disorder

Non‐trauma‐focused psychological intervention for PTSD and SUD or… showed no clear difference in treatment completers ‐ Group‐based intervention compared with control intervention (low certainty).

1 finding from 1 review

Non‐trauma‐focused psychological intervention for PTSD and SUD or PTSD only vs psychological interventions

Drug or alcohol use, or both following treatment completion ‐ Individual‐based intervention · Individuals with post‐traumatic stress disorder and comorbid substance use disorder
1 finding from 1 review

Non‐trauma‐focused psychological intervention for PTSD and SUD or PTSD only vs psychological interventions

Treatment completers · Individuals with post‐traumatic stress disorder and comorbid substance use disorder

It is very uncertain whether non‐trauma‐focused psychological intervention for PTSD and SUD or… changes treatment completers compared with active psychological intervention (very low certainty).

1 finding from 1 review

Trauma‐focused psychological intervention vs psychological interventions

Treatment completers · Individuals with post‐traumatic stress disorder and comorbid substance use disorder

Trauma‐focused psychological intervention showed no clear difference in treatment completers compared with active psychological intervention (low certainty).

1 finding from 1 review

Mindfulness‐based 'third wave' cognitive and behavioural therapies vs ALL OTHER PSYCHOLOGICAL THERAPIES

Clinical non‐response at post‐treatment · patients with depression

It is very uncertain whether mindfulness‐based 'third wave' cognitive and behavioural therapies changes clinical non‐response at post‐treatment compared with other psychological therapies (very low certainty).

1 finding from 1 review