Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

160 questions · 160 findings · 28 reviews · Vascular

No studies found 17 · 10.6%GRADE not reported 7 · 4.4%Very low 38 · 23.8%Low 56 · 35%Moderate 36 · 22.5%High 6 · 3.8%

Ultrasound‐assisted catheter‐directed thrombolysis plus standard intravenous heparinisation vs standard intravenous heparinisation

All‐cause mortality (90‐day) · people with intermediate‐risk (submassive) APE

It is very uncertain whether ultrasound‐assisted catheter‐directed thrombolysis plus standard… changes all‐cause mortality (90‐day) compared with standard intravenous heparinisation (very low certainty).

1 finding from 1 review

Clopidogrel vs placebo

Number of related surgical or radiological interventions · people with ESRD receiving haemodialysis through an arteriovenous fistula

Clopidogrel showed no clear difference in number of related surgical or radiological interventions (42 days) compared with placebo (moderate certainty).

1 finding from 1 review