Findings

What do systematic reviews say?

49 questions · 51 findings · 8 reviews · Neonatal

No studies found 0 · 0%GRADE not reported 4 · 7.8%Very low 8 · 15.7%Low 10 · 19.6%Moderate 21 · 41.2%High 8 · 15.7%

Ever diagnosed as asthmatic by 7 years of age · Preterm neonates with respiratory distress

The intervention probably leads to lower ever diagnosed as asthmatic by 7 years of age (moderate certainty).

1 finding from 1 review

Duration of mechanical ventilation (days) · Preterm neonates with respiratory distress

1 finding from 1 review

Duration of supplemental oxygen (days) · Preterm neonates with respiratory distress

1 finding from 1 review

Hyperglycaemia · Preterm neonates with respiratory distress

The intervention probably leads to lower hyperglycaemia (moderate certainty).

1 finding from 1 review

Patent ductus arteriosus · Preterm neonates with respiratory distress

The intervention probably leads to higher patent ductus arteriosus (moderate certainty).

1 finding from 1 review

BPD at 36 weeks' postmenstrual age · Preterm neonates with respiratory distress

The intervention showed no clear difference in BPD at 36 weeks' postmenstrual age (moderate certainty).

1 finding from 1 review

Death at hospital discharge · neonates with clinical and microbiological features of bacterial meningitis

It is very uncertain whether adjunctive steroid changes all‐cause death until hospital discharge compared with placebo (very low certainty).

1 finding from 1 review

Adjuvant corticosteroids for reducing death in neonatal bacterial meningitis 2015 · Cochrane Headline outcomes only
RR 0.46 [0.24, 0.88]
2 studies · 132 participants
Very low

Developmental delay at ≥ 18 months · neonates with clinical and microbiological features of bacterial meningitis

Adjunctive steroid showed no clear difference in number of participants with developmental delay compared with placebo (low certainty).

1 finding from 1 review

Adjuvant corticosteroids for reducing death in neonatal bacterial meningitis 2015 · Cochrane Headline outcomes only
RR 0.77 [0.32, 1.87]
1 study · 38 participants
Low

Hearing loss · neonates with clinical and microbiological features of bacterial meningitis

Adjunctive steroid showed no clear difference in hearing loss at 2 years of age compared with placebo (low certainty).

2 findings from 1 review

Adjuvant corticosteroids for reducing death in neonatal bacterial meningitis 2015 · Cochrane Headline outcomes only
RR 1.8 [0.18, 18.21]
1 study · 38 participants
Low
Adjuvant corticosteroids for reducing death in neonatal bacterial meningitis 2015 · Cochrane Headline outcomes only
RR 0.41 [0.17, 0.98]
1 study · 59 participants
Low