Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

56 questions · 56 findings · 4 reviews

No studies found 18 · 32.1%GRADE not reported 0 · 0%Very low 0 · 0%Low 16 · 28.6%Moderate 16 · 28.6%High 6 · 10.7%

Isradipine vs placebo

Death at the end of · people with acute ischemic stroke

Isradipine showed no clear difference in death at the end of compared with placebo (low certainty).

1 finding from 1 review

Nimodipine vs placebo

Death or dependency at end of · people with acute ischemic stroke

Nimodipine showed no clear difference in death or dependency at end of compared with placebo (moderate certainty).

1 finding from 1 review

Nimodipine vs placebo

Death at the end of treatment · people with acute ischemic stroke

Nimodipine showed no clear difference in death at the end of treatment compared with placebo (moderate certainty).

1 finding from 1 review

Flunarizine vs placebo

Adverse effects ‐ Blurred vision No of patients with blurred vision · patients with drug‐resistant epilepsy

Flunarizine showed no clear difference in adverse effects ‐ Blurred vision No of patients with blurred vision compared with placebo (high certainty).

1 finding from 1 review

Nimodipine vs placebo

50% or greater reduction in seizure frequency Number of seizures · patients with drug‐resistant epilepsy

Nimodipine showed no clear difference in 50% or greater reduction in seizure frequency Number of seizures compared with placebo (moderate certainty).

1 finding from 1 review