Proportion of mothers with serious adverse events ( · opiate‐dependent pregnant women
Methadone showed no clear difference in serious adverse events for the mother compared with buprenorphine (low certainty).
1 finding from 1 review
Serious adverse events for the child · opiate‐dependent pregnant women
Methadone showed no clear difference in serious adverse events for the child compared with buprenorphine (low certainty).
1 finding from 1 review
Abstinence · individuals dependent on illicit opiates
Dihydrocodeine showed no clear difference in abstinence Assessed by urinalysis post‐detoxification compared with buprenorphine (low certainty).
3 findings from 1 review
RR 0.42 [0.11, 1.57]
2 studies · 150 participants
Low
RR 0.59 [0.26, 1.31]
2 studies · 150 participants
Low
RR 0.59 [0.25, 1.39]
2 studies · 150 participants
Low
Serious adverse events or adverse events · individuals dependent on illicit opiates
1 finding from 1 review
Treatment retention Early dropout · individuals dependent on illicit opiates
Dihydrocodeine showed no clear difference in treatment retention Early dropout compared with buprenorphine (low certainty).
1 finding from 1 review
Heroin use and positive urine screen testing · 211 adults
1 finding from 1 review
Intervention not reported
Retention in treatment · People with opioid dependence.
The intervention leads to lower retention in treatment (high certainty).
1 finding from 1 review
Intervention not reported
Morphine‐positive urines · People with opioid dependence.
The intervention showed no clear difference in morphine‐positive urines (moderate certainty).
1 finding from 1 review
Intervention not reported
Self‐reported heroin use · People with opioid dependence.
The intervention showed no clear difference in self‐reported heroin use (moderate certainty).
1 finding from 1 review
Intervention not reported
Cocaine‐positive urines · People with opioid dependence.
The intervention showed no clear difference in cocaine‐positive urines (moderate certainty).
1 finding from 1 review
Intervention not reported
Benzodiazepine‐positive urines · People with opioid dependence.
The intervention showed no clear difference in benzodiazepine‐positive urines (moderate certainty).
1 finding from 1 review
Intervention not reported
Retention in treatment · People with opioid dependence.
The intervention leads to higher retention in treatment (high certainty).
1 finding from 1 review
Intervention not reported
Morphine‐positive urines · People with opioid dependence.
The intervention showed no clear difference in morphine‐positive urines (moderate certainty).
1 finding from 1 review
Intervention not reported
Benzodiazepine‐positive urines · People with opioid dependence.
The intervention showed no clear difference in benzodiazepine‐positive urines (moderate certainty).
1 finding from 1 review