Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

364 questions · 389 findings · 54 reviews

No studies found 95 · 24.4%GRADE not reported 40 · 10.3%Very low 45 · 11.6%Low 126 · 32.4%Moderate 76 · 19.5%High 7 · 1.8%

Multiple methods of breastfeeding support (including social, educational and/or physical support) vs usual care

Exclusive breastfeeding at 6 months · pregnant or lactating women who were overweight or obese

It is very uncertain whether multiple methods of breastfeeding support (including social,… changes exclusive breastfeeding at 6 months compared with usual care (very low certainty).

1 finding from 1 review

Non‐exclusive breastfeeding (foods) vs exclusive breastfeeding

“Food allergy” to 1 or more foods between 1 to 3 years of age · healthy breastfeeding full‐term infants

Non‐exclusive breastfeeding (foods) showed no clear difference in “Food allergy” to 1 or more foods between 1 to 3 years of age compared with exclusive breastfeeding (moderate certainty).

1 finding from 1 review

Non‐exclusive breastfeeding (foods) vs exclusive breastfeeding

Visible eczema at 12‐month visit stratified by visible eczema at enrolment · healthy breastfeeding full‐term infants

Non‐exclusive breastfeeding (foods) showed no clear difference in visible eczema at 12‐month visit stratified by visible eczema at… compared with exclusive breastfeeding (moderate certainty).

1 finding from 1 review

Non‐exclusive breastfeeding (foods) vs exclusive breastfeeding

Food protein enterocolitis syndrome positive response to challenge (number of children) · healthy breastfeeding full‐term infants

Non‐exclusive breastfeeding (foods) showed no clear difference in food protein enterocolitis syndrome positive response to challenge… compared with exclusive breastfeeding (moderate certainty).

1 finding from 1 review

Breastfeeding for <4 months vs Breastfeeding for ≥4 months

Early childhood caries (ECC) · Preschool children (<6 years)

Breastfeeding for <4 vs ≥4 months was not significantly associated with early childhood caries (RR 0.95, 95% CI 0.80-1.13; ungraded).

1 finding from 1 review

Breastfeeding for <6 months vs Breastfeeding for ≥6 months

Early childhood caries (ECC) · Preschool children (<6 years)

In cohort studies, breastfeeding for <6 vs ≥6 months was not significantly associated with early childhood caries (RR 0.97, 95% CI 0.88-1.06; ungraded).

2 findings from 1 review

Non‐exclusive breastfeeding (artificial milk) vs exclusive breastfeeding

Infant morbidity ‐ allergy symptoms ‐ Infants with allergy symptoms at 18 months of age · healthy breastfeeding full‐term infants

It is very uncertain whether non‐exclusive breastfeeding (artificial milk) changes infant morbidity ‐ allergy symptoms ‐ Infants with allergy symptoms… compared with exclusive breastfeeding (very low certainty).

1 finding from 1 review

Non‐exclusive breastfeeding (water or glucose water) vs exclusive breastfeeding

Hypoglycaemia episodes at 12 hours of life (glycaemia < 2.2 mmol/L) · healthy breastfeeding full‐term infants

It is very uncertain whether non‐exclusive breastfeeding (water or glucose water) changes hypoglycaemia episodes at 12 hours of life (glycaemia < 2.2 mmol/L) compared with exclusive breastfeeding (very low certainty).

1 finding from 1 review

Non‐exclusive breastfeeding (water or glucose water) vs exclusive breastfeeding

Hypoglycaemia episodes at 24 hours of life (glycaemia < 2.2 mmol/L) · healthy breastfeeding full‐term infants

It is very uncertain whether non‐exclusive breastfeeding (water or glucose water) changes hypoglycaemia episodes at 24 hours of life (glycaemia < 2.2 mmol/L) compared with exclusive breastfeeding (very low certainty).

1 finding from 1 review

Breastfeeding vs Bottle feeding

Dental caries · Children with exclusively primary dentition (age ≤71 months)

In a meta-analysis of two cross-sectional studies, breastfed children had lower odds of dental caries than bottle-fed children (OR 0.43, 95% CI 0.23 to 0.80); certainty was not formally graded.

2 findings from 1 review