Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

125 questions · 133 findings · 17 reviews

No studies found 23 · 17.3%GRADE not reported 14 · 10.5%Very low 28 · 21.1%Low 57 · 42.9%Moderate 11 · 8.3%High 0 · 0%

Attention deficit hyperactivity disorder (ADHD)‐related drugs vs placebo

Aggression · participants (any age) with a clinical diagnosis of ASD who have displayed one or more unwanted or challenging behaviours at baseline…

The review found no eligible studies for this question.

1 finding from 1 review

Attention deficit hyperactivity disorder (ADHD)‐related drugs vs placebo

Adverse effects · participants (any age) with a clinical diagnosis of ASD who have displayed one or more unwanted or challenging behaviours at baseline…

It is very uncertain whether attention deficit hyperactivity disorder (ADHD)‐related drugs changes adverse effects compared with placebo (very low certainty).

1 finding from 1 review

Child has a disability (special needs) vs Parents/caregivers of children without disabilities

Parental concern / caregiver stress indices (parental perception and parenting stress about the child's oral health) · Parents/caregivers of children with disabilities (special needs; autism spectrum disorder or unspecified disability) in Saudi Arabia

Parents of children with disabilities in Saudi Arabia report significantly greater concern/stress about their child's oral health than parents of children without disabilities (pooled SMD 0.43, 95% CI 0.23 to 0.63; I2=0%; 3 studies); not GRADE-rated.

1 finding from 1 review

Music therapy vs placebo or usual care

Global improvement · Individuals with autism spectrum disorder

Music therapy probably leads to higher global improvement compared with placebo therapy or standard care (moderate certainty).

1 finding from 1 review