Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

90 questions · 91 findings · 10 reviews · Eyes and Vision

No studies found 39 · 42.9%GRADE not reported 3 · 3.3%Very low 17 · 18.7%Low 19 · 20.9%Moderate 11 · 12.1%High 2 · 2.2%

Standard treatment plus systemic corticosteroids vs usual care

Duration of time requiring intravenous antibiotics · patients age 10 years and older with periorbital or orbital cellulitis

It is very uncertain whether standard treatment plus systemic corticosteroids changes duration of time requiring intravenous antibiotics compared with standard treatment alone (very low certainty).

1 finding from 1 review

Oral vs topical antibiotics

Active trachoma · people (any age) with active trachoma

Oral showed no clear difference in active trachoma Clinical assessment: active trachoma defined as TF,… compared with topical antibiotic (low certainty).

1 finding from 1 review

Vitrectomy vs vitreous tap biopsy and antibiotic injection

Improvement in visual acuity at 3 months' · people with endophthalmitis following intraocular surgery

It is very uncertain whether vitrectomy changes proportion of people with a visual acuity improvement of 10 letters… compared with vitreous tap biopsy and antibiotic injection (very low certainty).

1 finding from 1 review

Vitrectomy vs vitreous tap biopsy and antibiotic injection

Additional surgical procedure, including vitrectomy and cataract surgery. · people with endophthalmitis following intraocular surgery

Vitrectomy showed no clear difference in additional surgical procedure, including vitrectomy and cataract… compared with vitreous tap biopsy and antibiotic injection (low certainty).

1 finding from 1 review

Acupuncture vs topical antibiotics

Resolution of hordeolum at short term · people with acute hordeolum

Acupuncture may leads to higher resolution of hordeolum at short term compared with topical antibiotics (low certainty).

1 finding from 1 review