Findings

What do systematic reviews say?

146 questions · 153 findings · 11 reviews · ENT

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No studies found 62 · 40.5%GRADE not reported 1 · 0.7%Very low 58 · 37.9%Low 22 · 14.4%Moderate 8 · 5.2%High 2 · 1.3%

Topical antibiotics vs placebo/no treatment

Hearing · patients with mucopurulent otorrhoea

1 finding from 1 review

Topical antibiotics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 35 participants
Very low

Topical antibiotics vs placebo/no treatment

Serious complications · patients with mucopurulent otorrhoea

The review found no eligible studies for this question.

1 finding from 1 review

Topical antibiotics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical antibiotics vs placebo/no treatment

Suspected ototoxicity · patients with mucopurulent otorrhoea

1 finding from 1 review

Topical antibiotics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 35 participants
Very low

Topical antibiotics vs acetic acid

Resolution of ear discharge ‐ measured at 1 to 2 weeks · chronic suppurative otitis media

It is very uncertain whether topical antibiotics changes resolution of ear discharge (1 to 2 weeks) Aminoglycosides compared with acetic acid (very low certainty).

1 finding from 1 review

Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
RR 0.88 [0.72, 1.08]
1 study · 100 participants
Very low

Topical antibiotics vs acetic acid

Resolution of ear discharge ‐ measured after 4 weeks · chronic suppurative otitis media

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical antibiotics vs acetic acid

Quality of life ‐ not measured · chronic suppurative otitis media

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical antibiotics vs acetic acid

Ear pain (otalgia) or discomfort or local irritation · chronic suppurative otitis media

It is very uncertain whether topical antibiotics changes ear pain, discomfort, irritation compared with acetic acid (very low certainty).

1 finding from 1 review

Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
RR 0.16 [0.02, 1.34]
2 studies · 189 participants
Very low

Topical antibiotics vs acetic acid

Hearing · chronic suppurative otitis media

1 finding from 1 review

Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 107 participants
Very low

Topical antibiotics vs acetic acid

Serious complications ‐ not measured · chronic suppurative otitis media

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical antibiotics vs acetic acid

Suspected ototoxicity · chronic suppurative otitis media

It is very uncertain whether topical antibiotics changes suspected ototoxicity compared with acetic acid (very low certainty).

1 finding from 1 review

Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 100 participants
Very low

Antibiotics vs no treatment/placebo

Resolution of ear discharge ‐ measured at 1 to 2 weeks · children with CSOM

It is very uncertain whether systemic antibiotics changes resolution of ear discharge ‐ measured at 1 to 2 weeks compared with no treatment/placebo (very low certainty).

1 finding from 1 review

Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
RR 8.47 [1.88, 38.21]
1 study · 33 participants
Very low

Antibiotics vs no treatment/placebo

Resolution of ear discharge ‐ measured after 4 weeks · children with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antibiotics vs no treatment or placebo on top of topical antiseptics

Resolution of ear discharge ‐ measured at 1 to 2 weeks · schoolchildren with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antibiotics vs no treatment or placebo on top of topical antiseptics

Resolution of ear discharge ‐ measured after 4 weeks · schoolchildren with CSOM

It is very uncertain whether systemic antibiotics changes resolution of ear discharge (4 weeks or more) ‐ measured at 3 to 4… compared with no treatment or placebo on top of topical antiseptics (very low certainty).

1 finding from 1 review

Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
RR 1.03 [0.75, 1.41]
1 study · 136 participants
Very low

Antibiotics vs no treatment or placebo on top of topical antiseptics

Health‐related quality of life · schoolchildren with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antibiotics vs no treatment or placebo on top of topical antiseptics

Ear pain (otalgia) or discomfort or local irritation · schoolchildren with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antibiotics vs no treatment or placebo on top of topical antiseptics

Hearing · schoolchildren with CSOM

1 finding from 1 review

Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 204 participants
Very low

Antibiotics vs no treatment or placebo on top of topical antiseptics

Serious complications · schoolchildren with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antibiotics vs no treatment or placebo on top of topical antiseptics

Suspected ototoxicity · schoolchildren with CSOM

1 finding from 1 review

Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 204 participants
Very low

Antibiotics vs no treatment/placebo

Health‐related quality of life · children with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found