Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

86 questions · 97 findings · 12 reviews

No studies found 14 · 14.4%GRADE not reported 4 · 4.1%Very low 31 · 32%Low 29 · 29.9%Moderate 15 · 15.5%High 4 · 4.1%

Drug‐eluting balloon vs uncoated balloon angioplasty at 12 months

Amputation · people with peripheral arterial disease of the lower limbs

Drug‐eluting balloon showed no clear difference in amputation compared with uncoated balloon angioplasty at 12 months (high certainty).

1 finding from 1 review

Drug‐eluting balloon vs uncoated balloon angioplasty at 12 months

Primary vessel patency · people with peripheral arterial disease of the lower limbs

Drug‐eluting balloon leads to higher primary vessel patency compared with uncoated balloon angioplasty at 12 months (high certainty).

1 finding from 1 review

Drug‐eluting balloon vs uncoated balloon angioplasty at 12 months

Target lesion revascularization · people with peripheral arterial disease of the lower limbs

Drug‐eluting balloon may leads to lower target lesion revascularization compared with uncoated balloon angioplasty at 12 months (low certainty).

1 finding from 1 review

Drug‐eluting balloon vs uncoated balloon angioplasty at 12 months

Binary restenosis · people with peripheral arterial disease of the lower limbs

Drug‐eluting balloon probably leads to lower binary restenosis compared with uncoated balloon angioplasty at 12 months (moderate certainty).

1 finding from 1 review

Drug‐eluting balloon vs uncoated balloon angioplasty at 12 months

Death · people with peripheral arterial disease of the lower limbs

Drug‐eluting balloon showed no clear difference in death compared with uncoated balloon angioplasty at 12 months (high certainty).

1 finding from 1 review

Atherectomy vs balloon angioplasty with primary stenting

TVR ( · people with PAD

It is very uncertain whether atherectomy changes TVR ( compared with balloon angioplasty with primary stenting (very low certainty).

2 findings from 1 review