Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

101 questions · 107 findings · 14 reviews · Eyes and Vision

No studies found 32 · 29.9%GRADE not reported 5 · 4.7%Very low 28 · 26.2%Low 29 · 27.1%Moderate 10 · 9.3%High 3 · 2.8%

Laser‐assisted in‐situ keratomileusis (LASIK) vs photorefractive keratectomy (PRK)

Lost one or more lines of BCVA · patients with myopia

Laser‐assisted in‐situ keratomileusis (LASIK) showed no clear difference in lost one or more lines of BCVA compared with photorefractive keratectomy (PRK) (low certainty).

1 finding from 1 review

Laser‐assisted in‐situ keratomileusis (LASIK) vs photorefractive keratectomy (PRK)

Final BCVA of 20/40 or less · patients with myopia

It is very uncertain whether laser‐assisted in‐situ keratomileusis (LASIK) changes final BCVA of 20/40 or less compared with photorefractive keratectomy (PRK) (very low certainty).

1 finding from 1 review

Silicone hydrogel vs hydrogel soft contact lenses

Comfort · Adults with refractive errors

The review found no eligible studies for this question.

3 findings from 1 review

Silicone hydrogel vs hydrogel soft contact lenses

Proportion of participants who discontinued contact lens wear, at 1 week (RR < 1 favored) · Adults with refractive errors

It is very uncertain whether silicone hydrogel changes proportion of participants who discontinued contact lens wear, at 1… compared with hydrogel soft contact lenses (very low certainty).

1 finding from 1 review

Silicone hydrogel vs hydrogel soft contact lenses

Corneal staining scores, at 1 week (MD < 0 favored) · Adults with refractive errors

It is very uncertain whether silicone hydrogel changes corneal staining scores, at 1 week (MD < 0 favored) compared with hydrogel soft contact lenses (very low certainty).

1 finding from 1 review

Silicone hydrogel vs hydrogel soft contact lenses

Conjunctival staining scores, at 1 month (MD < 0 favored) · Adults with refractive errors

It is very uncertain whether silicone hydrogel changes conjunctival staining scores, at 1 month (MD < 0 favored) compared with hydrogel soft contact lenses (very low certainty).

1 finding from 1 review

NSAIDs vs placebo or active control

Visual improvement at end of treatment, as defined by two or more Snellen lines · participants with acute CME (< 4 months) following cataract surgery

It is very uncertain whether NSAID changes visual improvement at end of treatment, as defined by two or more… compared with placebo or active control (very low certainty).

1 finding from 1 review

NSAIDs vs active control

Visual improvement at end of treatment, as defined by two or more Snellen lines · participants with acute or chronic CME following cataract surgery

It is very uncertain whether NSAID changes visual improvement at end of treatment, as defined by two or more… compared with active control (very low certainty).

1 finding from 1 review