Findings

What do systematic reviews say?

601 questions · 608 findings · 50 reviews · Kidney and Transplant

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No studies found 127 · 20.9%GRADE not reported 6 · 1%Very low 189 · 31.1%Low 184 · 30.3%Moderate 87 · 14.3%High 15 · 2.5%

Pre‐emptive medication for cytomegalovirus (CMV) viraemia vs placebo/no treatment

Graft loss · solid organ transplant recipients with CMV viraemia

1 finding from 1 review

Pre‐emptive treatment for cytomegalovirus viraemia to prevent cytomegalovirus disease in solid organ transplant… 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 36 participants
Very low

Pre‐emptive medication for cytomegalovirus (CMV) viraemia vs placebo/no treatment

Leucopenia · solid organ transplant recipients with CMV viraemia

1 finding from 1 review

Pre‐emptive treatment for cytomegalovirus viraemia to prevent cytomegalovirus disease in solid organ transplant… 2013 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 114 participants
Low

rhGH 28 IU/m²/wk vs placebo/no treatment

HSDS after 1 year of rhGH · children with chronic kidney disease

1 finding from 1 review

Growth hormone for children with chronic kidney disease 2012 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 331 participants
Moderate

rhGH 28 IU/m²/wk vs placebo/no treatment

Height velocity (cm/year) · children with chronic kidney disease

2 findings from 1 review

Growth hormone for children with chronic kidney disease 2012 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 27 participants
Low
Growth hormone for children with chronic kidney disease 2012 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 287 participants
Moderate

rhGH 28 IU/m²/wk vs placebo/no treatment

Change in height velocity SDS from baseline to 6 months · children with chronic kidney disease

1 finding from 1 review

Growth hormone for children with chronic kidney disease 2012 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 27 participants
Low

rhGH 28 IU/m²/wk vs placebo/no treatment

Change in height velocity SDS (difference between baseline and final visit at one year) · children with chronic kidney disease

1 finding from 1 review

Growth hormone for children with chronic kidney disease 2012 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 22 participants
Low

Vitamin D vs placebo/no treatment

PTH · patients with bone disease in children with chronic kidney disease

1 finding from 1 review

Interventions for bone disease in children with chronic kidney disease 2010 · Cochrane Headline outcomes only
no estimate extracted
1 study · 12 participants
Low

Vitamin D vs placebo/no treatment

Number without 30% fall in PTH on two occasions · patients with bone disease in children with chronic kidney disease

Vitamin D preparations may leads to lower number without 30% fall in PTH on two occasions compared with placebo/no treatment (low certainty).

1 finding from 1 review

Interventions for bone disease in children with chronic kidney disease 2010 · Cochrane Headline outcomes only
RR 0.6 [0.4, 0.89]
2 studies · 76 participants
Low

Vitamin D vs placebo/no treatment

Hypercalcaemia · patients with bone disease in children with chronic kidney disease

1 finding from 1 review

Interventions for bone disease in children with chronic kidney disease 2010 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 103 participants
Low

Vitamin D vs placebo/no treatment

Change in calcium‐phosphorus product mg(2)/dL(2) · patients with bone disease in children with chronic kidney disease

1 finding from 1 review

Interventions for bone disease in children with chronic kidney disease 2010 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 76 participants
Moderate

Calcium channel blockers vs placebo/no treatment

Death · kidney transplant recipients

Calcium channel blockers showed no clear difference in death compared with placebo/no treatment (low certainty).

1 finding from 1 review

Antihypertensive treatment for kidney transplant recipients 2009 · Cochrane Headline outcomes only
RR 0.82 [0.37, 1.82]
12 studies · 792 participants
Low

Angiotensin‐converting enzyme inhibitors vs placebo/no treatment

GFR · kidney transplant recipients

1 finding from 1 review

Antihypertensive treatment for kidney transplant recipients 2009 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 77 participants
Low

Angiotensin‐converting enzyme inhibitors vs placebo/no treatment

Proteinuria · kidney transplant recipients

1 finding from 1 review

Antihypertensive treatment for kidney transplant recipients 2009 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 175 participants
Moderate

Angiotensin‐converting enzyme inhibitors vs placebo/no treatment

Serum creatinine (mg/dL) · kidney transplant recipients

1 finding from 1 review

Antihypertensive treatment for kidney transplant recipients 2009 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 272 participants
Low

Angiotensin‐converting enzyme inhibitors vs placebo/no treatment

Haemoglobin (g/dL) · kidney transplant recipients

1 finding from 1 review

Antihypertensive treatment for kidney transplant recipients 2009 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 191 participants
Moderate

Angiotensin‐converting enzyme inhibitors vs placebo/no treatment

Blood pressure · kidney transplant recipients

1 finding from 1 review

Antihypertensive treatment for kidney transplant recipients 2009 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 392 participants
Very low

Calcium channel blockers vs placebo/no treatment

Graft loss · kidney transplant recipients

Calcium channel blockers may leads to lower graft loss compared with placebo/no treatment (low certainty).

1 finding from 1 review

Antihypertensive treatment for kidney transplant recipients 2009 · Cochrane Headline outcomes only
RR 0.75 [0.57, 0.99]
17 studies · 1255 participants
Low

Calcium channel blockers vs placebo/no treatment

GFR · kidney transplant recipients

1 finding from 1 review

Antihypertensive treatment for kidney transplant recipients 2009 · Cochrane Headline outcomes only
no estimate extracted
18 studies · 1119 participants
Moderate

Calcium channel blockers vs placebo/no treatment

Acute rejection · kidney transplant recipients

Calcium channel blockers showed no clear difference in acute rejection compared with placebo/no treatment (low certainty).

1 finding from 1 review

Antihypertensive treatment for kidney transplant recipients 2009 · Cochrane Headline outcomes only
RR 1.02 [0.85, 1.23]
11 studies · 771 participants
Low

Calcium channel blockers vs placebo/no treatment

Discontinuation of treatment due to side effects ( · kidney transplant recipients

Calcium channel blockers showed no clear difference in withdrawal due to side effects compared with placebo/no treatment (low certainty).

1 finding from 1 review

Antihypertensive treatment for kidney transplant recipients 2009 · Cochrane Headline outcomes only
RR 0.99 [0.53, 1.87]
2 studies · 156 participants
Low