Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,156 questions · 1,179 findings · 198 reviews · Headline outcomes only

No studies found 250 · 21.2%GRADE not reported 43 · 3.6%Very low 236 · 20%Low 395 · 33.5%Moderate 208 · 17.6%High 47 · 4%

Cannabis‐based medicines vs placebo medication

Daily breakthrough opioid dosage (mg morphine equivalent) · adults with cancer‐related pain

Cannabis‐based medicines showed no clear difference in daily breakthrough opioid dosage (mg morphine equivalent) compared with placebo medication (moderate certainty).

1 finding from 1 review

Laser trabeculoplasty vs medication

Failure to stabilise visual field progression (as defined by study investigators) · people with open‐angle glaucoma

Laser trabeculoplasty showed no clear difference in failure to stabilise visual field progression (as defined by study… compared with medication (moderate certainty).

1 finding from 1 review

Laser trabeculoplasty vs medication

Failure to stabilise optic neuropathy progression (as defined by study investigators) · people with open‐angle glaucoma

It is very uncertain whether laser trabeculoplasty changes failure to stabilise optic neuropathy progression (as defined by… compared with medication (very low certainty).

1 finding from 1 review

Acupuncture vs medication

Overactive bladder symptoms cured or improved · Adults with overactive bladder (OAB)

Acupuncture may leads to higher overactive bladder symptoms cured or improved compared with medication (low certainty).

1 finding from 1 review

Acupuncture vs medication

Presence or absence of urinary urgency · Adults with overactive bladder (OAB)

It is very uncertain whether acupuncture changes presence or absence of urinary urgency compared with medication (very low certainty).

1 finding from 1 review

Acupuncture vs medication

Episodes of urinary incontinence in a 24‐hour period · Adults with overactive bladder (OAB)

It is very uncertain whether acupuncture changes episodes of urinary incontinence in a 24‐hour period compared with medication (very low certainty).

1 finding from 1 review