Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

634 questions · 662 findings · 83 reviews

No studies found 177 · 26.7%GRADE not reported 97 · 14.7%Very low 182 · 27.5%Low 114 · 17.2%Moderate 66 · 10%High 26 · 3.9%

Risk‐reducing salpingo‐oophorectomy (RRSO) vs no RRSO according to BRCA mutation status

HGSC mortality: BRCA1 only

It is very uncertain whether risk‐reducing salpingo‐oophorectomy (RRSO) changes HGSC mortality: BRCA1 only compared with no RRSO according to BRCA mutation status (very low certainty).

1 finding from 1 review

Risk‐reducing salpingo‐oophorectomy (RRSO) vs no RRSO according to BRCA mutation status

Breast cancer mortality: BRCA1 only

It is very uncertain whether risk‐reducing salpingo‐oophorectomy (RRSO) changes breast cancer mortality: BRCA1 only compared with no RRSO according to BRCA mutation status (very low certainty).

1 finding from 1 review

Risk‐reducing salpingo‐oophorectomy (RRSO) vs no RRSO according to BRCA mutation status

Breast cancer mortality: BRCA2 only

It is very uncertain whether risk‐reducing salpingo‐oophorectomy (RRSO) changes breast cancer mortality: BRCA2 only compared with no RRSO according to BRCA mutation status (very low certainty).

1 finding from 1 review