What do systematic reviews say?

Oral irrigation plus toothbrushing vs Flossing plus toothbrushing

It is very uncertain whether oral irrigation plus toothbrushing changes plaque compared with flossing plus toothbrushing (very low certainty).

• Home use of interdental cleaning devices, in addition to toothbrushing, for preventing and controlling periodontal… 2019 · Cochrane All outcomes

  1 month
  SMD 0.31 [-0.08, 0.70]
  2 studies · 133 participants
  Very low

Rubber/elastomeric cleaning stick plus toothbrushing vs Interdental brushing plus toothbrushing

• Home use of interdental cleaning devices, in addition to toothbrushing, for preventing and controlling periodontal… 2019 · Cochrane All outcomes
  Two studies measured periodontitis but data not presented or usable (Smith 1988 PPD unusable; Graziani 2017 measured PPD but no data).
  2 studies
  GRADE not reported

Oral irrigation plus toothbrushing vs Toothbrushing alone

The review found no eligible studies for this question.

• Home use of interdental cleaning devices, in addition to toothbrushing, for preventing and controlling periodontal… 2019 · Cochrane All outcomes
  No included study assessed caries as an outcome.
  0 studies
  No studies found

Rubber/elastomeric cleaning stick plus toothbrushing vs Toothbrushing alone

The review found no eligible studies for this question.

• Home use of interdental cleaning devices, in addition to toothbrushing, for preventing and controlling periodontal… 2019 · Cochrane All outcomes
  No included study assessed caries as an outcome.
  0 studies
  No studies found

Interdental brushing plus toothbrushing vs Flossing plus toothbrushing

Interdental brushing plus toothbrushing showed no clear difference in periodontitis (probing pocket depth) compared with flossing plus toothbrushing (low certainty).

• Home use of interdental cleaning devices, in addition to toothbrushing, for preventing and controlling periodontal… 2019 · Cochrane All outcomes

  4 to 6 weeks
  MD -0.06 [-0.27, 0.16]
  3 studies · 107 participants
  Low

Wooden cleaning stick plus toothbrushing vs Toothbrushing alone

The review found no eligible studies for this question.

• Home use of interdental cleaning devices, in addition to toothbrushing, for preventing and controlling periodontal… 2019 · Cochrane All outcomes
  No included study assessed periodontitis as an outcome.
  0 studies
  No studies found

Oral irrigation plus toothbrushing vs Flossing plus toothbrushing

The review found no eligible studies for this question.

• Home use of interdental cleaning devices, in addition to toothbrushing, for preventing and controlling periodontal… 2019 · Cochrane All outcomes
  No included study assessed caries as an outcome.
  0 studies
  No studies found

Wooden cleaning stick plus toothbrushing vs Flossing plus toothbrushing

The review found no eligible studies for this question.

• Home use of interdental cleaning devices, in addition to toothbrushing, for preventing and controlling periodontal… 2019 · Cochrane All outcomes
  No included study assessed caries as an outcome.
  0 studies
  No studies found

Flossing plus toothbrushing vs Toothbrushing alone

• Home use of interdental cleaning devices, in addition to toothbrushing, for preventing and controlling periodontal… 2019 · Cochrane All outcomes
  One study measured probing pocket depth but no data were reported (Graziani 2017).
  1 study
  GRADE not reported

Oral irrigation plus toothbrushing vs Flossing plus toothbrushing

• Home use of interdental cleaning devices, in addition to toothbrushing, for preventing and controlling periodontal… 2019 · Cochrane All outcomes
  Both studies reported that there were no adverse events in either study group.
  2 studies
  GRADE not reported

Interdental brushing plus toothbrushing vs Flossing plus toothbrushing

• Home use of interdental cleaning devices, in addition to toothbrushing, for preventing and controlling periodontal… 2019 · Cochrane All outcomes
  Five studies reported there were no adverse events. Two studies reported on problems with the use of interdental brushes or floss, which sometimes caused soreness. (Six studies reported on adverse events; none…
  6 studies
  GRADE not reported

Supervised exercise therapy vs walking advice

• Supervised exercise therapy versus home‐based exercise therapy versus walking advice for intermittent claudication 2018 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 483 participants
  High

Supervised exercise therapy vs walking advice

• Supervised exercise therapy versus home‐based exercise therapy versus walking advice for intermittent claudication 2018 · Cochrane Headline outcomes only
  no estimate extracted
  7 studies · 624 participants
  High

Supervised exercise therapy vs walking advice

• Supervised exercise therapy versus home‐based exercise therapy versus walking advice for intermittent claudication 2018 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 508 participants
  High

Supervised exercise therapy vs walking advice

• Supervised exercise therapy versus home‐based exercise therapy versus walking advice for intermittent claudication 2018 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 296 participants
  Low

Supervised exercise therapy vs walking advice

• Supervised exercise therapy versus home‐based exercise therapy versus walking advice for intermittent claudication 2018 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 296 participants
  Low

Intervention not reported

• Home parenteral nutrition for people with inoperable malignant bowel obstruction 2018 · Cochrane Headline outcomes only
  no estimate extracted
  13 studies · 721 participants
  Very low

Intervention not reported

• Home parenteral nutrition for people with inoperable malignant bowel obstruction 2018 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 188 participants
  Very low

Intervention not reported

• Home parenteral nutrition for people with inoperable malignant bowel obstruction 2018 · Cochrane Headline outcomes only
  no estimate extracted
  9 studies · 280 participants
  Very low

Intervention not reported

The intervention showed no clear difference in mortality (3 ‐ 6 month (moderate certainty).

• Early discharge hospital at home 2017 · Cochrane Headline outcomes only
  RR 0.92 [0.57, 1.48]
  11 studies · 1114 participants
  Moderate