Cochrane · systematic review · CD005263

Supervised exercise therapy versus home‐based exercise therapy versus walking advice for intermittent claudication

Hageman, D, Fokkenrood, HJP, Gommans, LNM, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library

VascularAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
15
current version
GRADE rated
15
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 3 · 20%Low 5 · 33.3%Moderate 4 · 26.7%High 3 · 20%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Supervised exercise therapy versus home‐based exercise therapy for intermittent claudication

Population: patients with intermittent claudication
5 questions
OutcomeEffectEvidenceStatus / GRADE
Maximal treadmill walking distance after 3 months
Supervised exercise therapy vs home‐based exercise therapy
no estimate extracted8 studies · 351 participantsModerate
Downgraded: imprecision
Pain‐free treadmill walking distance after 3 months
Supervised exercise therapy vs home‐based exercise therapy
no estimate extracted7 studies · 322 participantsModerate
Downgraded: imprecision
Quality of life ‐ physical after 3 months (Short Form 36 physical component summary) Scale: 1 to 100 (higher scores indicate better quality of life)
Supervised exercise therapy vs home‐based exercise therapy
no estimate extracted2 studies · 68 participantsLow
Downgraded: risk of bias, imprecision
Quality of life ‐ mental after 3 months (Short Form 36 mental component summary) Scale: 1 to 100 (higher scores indicate better quality of life)
Supervised exercise therapy vs home‐based exercise therapy
no estimate extracted2 studies · 68 participantsLow
Downgraded: risk of bias, imprecision
Self‐reported functional impairment after 3 months (Walking Impairment Questionnaire combined) Scale: 1 to 100 (higher scores indicate better walking)
Supervised exercise therapy vs home‐based exercise therapy
no estimate extracted1 study · 62 participantsVery low
Downgraded: risk of bias, imprecision

Supervised exercise therapy versus walking advice for intermittent claudication

Population: patients with intermittent claudication
5 questions
OutcomeEffectEvidenceStatus / GRADE
Maximal treadmill walking distance after 3 months
Supervised exercise therapy vs walking advice
no estimate extracted7 studies · 624 participantsHigh
Pain‐free treadmill walking distance after 3 months
Supervised exercise therapy vs walking advice
no estimate extracted4 studies · 508 participantsHigh
Quality of life ‐ physical after 3 months (Short Form 36 physical component summary) Scale: 1 to 100 (higher scores indicate better quality of life)
Supervised exercise therapy vs walking advice
no estimate extracted2 studies · 296 participantsLow
Downgraded: risk of bias, imprecision
Quality of life ‐ mental after 3 months (Short Form 36 mental component summary) Scale: 1 to 100 (higher scores indicate better quality of life)
Supervised exercise therapy vs walking advice
no estimate extracted2 studies · 296 participantsLow
Downgraded: risk of bias, imprecision
Self‐reported functional impairment after 3 months (Walking Impairment Questionnaire combined) Scale: 1 to 100 (higher scores indicate better walking)
Supervised exercise therapy vs walking advice
no estimate extracted4 studies · 483 participantsHigh

Home‐based exercise therapy versus walking advice for intermittent claudication

Population: patients with intermittent claudication
5 questions
OutcomeEffectEvidenceStatus / GRADE
Maximal treadmill walking distance after 3 months
Home‐based exercise therapy vs walking advice
no estimate extracted4 studies · 137 participantsModerate
Downgraded: imprecision
Pain‐free treadmill walking distance after 3 months
Home‐based exercise therapy vs walking advice
no estimate extracted3 studies · 107 participantsLow
Downgraded: imprecision, inconsistency
Quality of life ‐ physical after 3 months (Short Form 36 physical component summary) Scale: 1 to 100 (higher scores indicate better quality of life)
Home‐based exercise therapy vs walking advice
no estimate extracted1 study · 20 participantsVery low
Downgraded: risk of bias, imprecision
Quality of life ‐ mental after 3 months (Short Form 36 mental component summary) Scale: 1 to 100 (higher scores indicate better quality of life)
Home‐based exercise therapy vs walking advice
no estimate extracted1 study · 20 participantsVery low
Downgraded: risk of bias, imprecision
Self‐reported functional impairment after 3 months (Walking Impairment Questionnaire combined) Scale: 1 to 100 (higher scores indicate better walking)
Home‐based exercise therapy vs walking advice
no estimate extracted2 studies · 79 participantsModerate
Downgraded: imprecision