Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,805 questions · 2,912 findings · 307 reviews · Headline outcomes only

No studies found 706 · 24.2%GRADE not reported 133 · 4.6%Very low 786 · 27%Low 696 · 23.9%Moderate 474 · 16.3%High 117 · 4%

Intermittent use of iron supplements vs placebo or no intervention

Iron deficiency (using ferritin concentrations) · children under 12 years of age

It is very uncertain whether intermittent use of iron supplements changes iron deficiency (using ferritin concentrations) compared with placebo or no intervention (very low certainty).

1 finding from 1 review

Intermittent use of iron supplements vs placebo or no intervention

Iron status (ferritin concentrations in ng/mL) · children under 12 years of age

Intermittent use of iron supplements may leads to higher iron status (ferritin (μg/L) compared with placebo or no intervention (low certainty).

1 finding from 1 review

Intermittent vs any daily iron supplementation

Iron deficiency (using ferritin concentrations) · children under 12 years of age

It is very uncertain whether intermittent changes iron deficiency (using ferritin concentrations) compared with daily use of iron supplements (very low certainty).

1 finding from 1 review

Surgical vs non‐surgical treatment

Complications requiring unplanned return to theatre Subtalar arthrodesis · people aged over 14 years with displaced intra‐articular calcaneal fractures

Surgical showed no clear difference in complications requiring unplanned return to theatre Subtalar… compared with non‐surgical management (low certainty).

1 finding from 1 review