Cochrane · systematic review · CD004977
Pneumococcal conjugate vaccines for preventing vaccine‐type invasive pneumococcal disease and X‐ray defined pneumonia in children less than two years of age
Lucero, MG, Dulalia, VE, Nillos, LT, et al. · Cochrane Database of Systematic Reviews · 2009 · Cochrane Library
Acute Respiratory InfectionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 2 · 50%High 2 · 50%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Comparison
Population: Children under two years of age
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
VT‐IPD, ITT (random) ( | RR 0.2 [0.1, 0.42] | 7 studies · 113044 participants | High |
All serotypes‐IPD, ITT (random) ( | RR 0.42 [0.25, 0.71] | 7 studies · 113044 participants | High |
X‐ray defined pneumonia, ITT (random) ( | RR 0.73 [0.64, 0.85] | 4 studies · 104755 participants | Moderate Downgraded: imprecision |
Clinical pneumonia, ITT (random) ( | RR 0.94 [0.91, 0.98] | 4 studies · 104755 participants | Moderate Downgraded: imprecision |