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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

1,558 questions in 115 reviews · Vascular

current versions
No studies 346 · 22.2%Ungraded 90 · 5.8%Very low 281 · 18%Low 477 · 30.6%Moderate 313 · 20.1%High 51 · 3.3%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
NMES vs GCS
Symptomatic DVT · participants at risk of venous thromboembolism
Neuromuscular electrical stimulation for the prevention of venous thromboembolism (2017) · Cochrane
no estimate extracted1 study · 36 participantsUngraded
NMES vs alternative prophylaxis
PE · participants at risk of venous thromboembolism
Neuromuscular electrical stimulation for the prevention of venous thromboembolism (2017) · Cochrane
OR 1.31 [0.38, 4.48]2 studies · 126 participantsLow
NMES vs GCS
PE · participants at risk of venous thromboembolism
Neuromuscular electrical stimulation for the prevention of venous thromboembolism (2017) · Cochrane
OR 0.32 [0.01, 8.27]1 study · 36 participantsLow
NMES vs GCS
Total VTE · participants at risk of venous thromboembolism
Neuromuscular electrical stimulation for the prevention of venous thromboembolism (2017) · Cochrane
no estimate extracted1 study · 36 participantsUngraded
NMES vs GCS
Bleeding (major and minor) · participants at risk of venous thromboembolism
Neuromuscular electrical stimulation for the prevention of venous thromboembolism (2017) · Cochrane
no estimate extracted1 study · 36 participantsUngraded
NMES vs IPCD
Total DVT · participants at risk of venous thromboembolism
Neuromuscular electrical stimulation for the prevention of venous thromboembolism (2017) · Cochrane
no estimate extracted1 study · 36 participantsLow
NMES vs IPCD
Asymptomatic DVT · participants at risk of venous thromboembolism
Neuromuscular electrical stimulation for the prevention of venous thromboembolism (2017) · Cochrane
no estimate extracted1 study · 36 participantsUngraded
NMES vs IPCD
Symptomatic DVT · participants at risk of venous thromboembolism
Neuromuscular electrical stimulation for the prevention of venous thromboembolism (2017) · Cochrane
no estimate extracted1 study · 36 participantsUngraded
NMES vs IPCD
PE · participants at risk of venous thromboembolism
Neuromuscular electrical stimulation for the prevention of venous thromboembolism (2017) · Cochrane
no estimate extracted1 study · 36 participantsLow
NMES vs IPCD
Total VTE · participants at risk of venous thromboembolism
Neuromuscular electrical stimulation for the prevention of venous thromboembolism (2017) · Cochrane
no estimate extracted1 study · 36 participantsUngraded
NMES vs IPCD
Bleeding (major and minor) · participants at risk of venous thromboembolism
Neuromuscular electrical stimulation for the prevention of venous thromboembolism (2017) · Cochrane
no estimate extracted1 study · 36 participantsUngraded
NMES vs alternative prophylaxis
Total VTE · participants at risk of venous thromboembolism
Neuromuscular electrical stimulation for the prevention of venous thromboembolism (2017) · Cochrane
OR 0.92 [0.34, 2.52]1 study · 72 participantsLow
NMES vs alternative prophylaxis
Bleeding (major and minor) · participants at risk of venous thromboembolism
Neuromuscular electrical stimulation for the prevention of venous thromboembolism (2017) · Cochrane
no estimate extracted6 studies · 415 participantsUngraded
NMES vs no prophylaxis
Total DVT · participants at risk of venous thromboembolism
Neuromuscular electrical stimulation for the prevention of venous thromboembolism (2017) · Cochrane
OR 0.4 [0.23, 0.7]4 studies · 576 participantsModerate
NMES vs no prophylaxis
Asymptomatic DVT · participants at risk of venous thromboembolism
Neuromuscular electrical stimulation for the prevention of venous thromboembolism (2017) · Cochrane
OR 0.32 [0.06, 1.62]1 study · 200 participantsLow
NMES vs no prophylaxis
Symptomatic DVT · participants at risk of venous thromboembolism
Neuromuscular electrical stimulation for the prevention of venous thromboembolism (2017) · Cochrane
OR 0.06 [0, 1.36]1 study · 160 participantsLow
Fondaparinux plus vitamin K antagonist vs standard therapy
Recurrent venous thromboembolism · people > 18 years of age with a diagnosed deep vein thrombosis
Pentasaccharides for the treatment of deep vein thrombosis (2017) · Cochrane
RR 0.8 [0.43, 1.47]2 studies · 2658 participantsModerate
Idrabiotaparinux vs idraparinux
All‐cause mortality · people > 18 years of age with a diagnosed deep vein thrombosis
Pentasaccharides for the treatment of deep vein thrombosis (2017) · Cochrane
RR 0.48 [0.18, 1.27]1 study · 757 participantsLow
Idrabiotaparinux vs idraparinux
Heparin‐induced thrombocytopenia ‐ not reported · people > 18 years of age with a diagnosed deep vein thrombosis
Pentasaccharides for the treatment of deep vein thrombosis (2017) · Cochrane
no estimate extractedNRNo studies
Idrabiotaparinux vs idraparinux
All harmful effects · people > 18 years of age with a diagnosed deep vein thrombosis
Pentasaccharides for the treatment of deep vein thrombosis (2017) · Cochrane
RR 0.92 [0.83, 1.02]1 study · 757 participantsVery low
Low molecular weight heparin and idraparinux vs standard therapy
Recurrent venous thromboembolism · people > 18 years of age with a diagnosed deep vein thrombosis
Pentasaccharides for the treatment of deep vein thrombosis (2017) · Cochrane
RR 1.51 [0.26, 8.9]1 study · 263 participantsVery low
Low molecular weight heparin and idraparinux vs standard therapy
Major bleeding during the initial treatment · people > 18 years of age with a diagnosed deep vein thrombosis
Pentasaccharides for the treatment of deep vein thrombosis (2017) · Cochrane
no estimate extractedNRNo studies
Low molecular weight heparin and idraparinux vs standard therapy
Major bleeding · people > 18 years of age with a diagnosed deep vein thrombosis
Pentasaccharides for the treatment of deep vein thrombosis (2017) · Cochrane
RR 3.76 [0.5, 28.19]1 study · 659 participantsVery low
Low molecular weight heparin and idraparinux vs standard therapy
All‐cause mortality · people > 18 years of age with a diagnosed deep vein thrombosis
Pentasaccharides for the treatment of deep vein thrombosis (2017) · Cochrane
no estimate extractedNRNo studies
Low molecular weight heparin and idraparinux vs standard therapy
Heparin‐induced thrombocytopenia · people > 18 years of age with a diagnosed deep vein thrombosis
Pentasaccharides for the treatment of deep vein thrombosis (2017) · Cochrane
no estimate extractedNRNo studies
Low molecular weight heparin and idraparinux vs standard therapy
All harmful effects · people > 18 years of age with a diagnosed deep vein thrombosis
Pentasaccharides for the treatment of deep vein thrombosis (2017) · Cochrane
no estimate extractedNRNo studies
Idraparinux vs standard therapy
Recurrent venous thromboembolism · people > 18 years of age with a diagnosed deep vein thrombosis
Pentasaccharides for the treatment of deep vein thrombosis (2017) · Cochrane
RR 0.98 [0.64, 1.48]1 study · 2904 participantsLow
Fondaparinux plus vitamin K antagonist vs standard therapy
Major bleeding during the initial treatment · people > 18 years of age with a diagnosed deep vein thrombosis
Pentasaccharides for the treatment of deep vein thrombosis (2017) · Cochrane
RR 1.15 [0.39, 3.44]2 studies · 2645 participantsModerate
Idraparinux vs standard therapy
Major bleeding during the initial treatment · people > 18 years of age with a diagnosed deep vein thrombosis
Pentasaccharides for the treatment of deep vein thrombosis (2017) · Cochrane
no estimate extractedNRNo studies
Idraparinux vs standard therapy
Major bleeding · people > 18 years of age with a diagnosed deep vein thrombosis
Pentasaccharides for the treatment of deep vein thrombosis (2017) · Cochrane
RR 0.71 [0.34, 1.47]1 study · 2904 participantsVery low
Idraparinux vs standard therapy
All‐cause mortality · people > 18 years of age with a diagnosed deep vein thrombosis
Pentasaccharides for the treatment of deep vein thrombosis (2017) · Cochrane
RR 1.14 [0.69, 1.86]1 study · 2904 participantsLow
Idraparinux vs standard therapy
Heparin‐induced thrombocytopenia · people > 18 years of age with a diagnosed deep vein thrombosis
Pentasaccharides for the treatment of deep vein thrombosis (2017) · Cochrane
no estimate extractedNRNo studies
Idraparinux vs standard therapy
All harmful effects · people > 18 years of age with a diagnosed deep vein thrombosis
Pentasaccharides for the treatment of deep vein thrombosis (2017) · Cochrane
RR 1.03 [1, 1.06]1 study · 2904 participantsVery low
Fondaparinux plus vitamin K antagonist vs standard therapy
Major bleeding · people > 18 years of age with a diagnosed deep vein thrombosis
Pentasaccharides for the treatment of deep vein thrombosis (2017) · Cochrane
RR 1.05 [0.64, 1.71]2 studies · 2645 participantsModerate
Fondaparinux plus vitamin K antagonist vs standard therapy
All‐cause mortality · people > 18 years of age with a diagnosed deep vein thrombosis
Pentasaccharides for the treatment of deep vein thrombosis (2017) · Cochrane
RR 0.93 [0.45, 1.91]2 studies · 2645 participantsModerate
Fondaparinux plus vitamin K antagonist vs standard therapy
Heparin‐induced thrombocytopenia ‐ not measured · people > 18 years of age with a diagnosed deep vein thrombosis
Pentasaccharides for the treatment of deep vein thrombosis (2017) · Cochrane
no estimate extractedNRNo studies
Fondaparinux plus vitamin K antagonist vs standard therapy
All harmful effects · people > 18 years of age with a diagnosed deep vein thrombosis
Pentasaccharides for the treatment of deep vein thrombosis (2017) · Cochrane
RR 0.84 [0.76, 0.93]1 study · 2192 participantsVery low
Idrabiotaparinux vs idraparinux
Recurrent venous thromboembolism · people > 18 years of age with a diagnosed deep vein thrombosis
Pentasaccharides for the treatment of deep vein thrombosis (2017) · Cochrane
RR 0.72 [0.31, 1.69]1 study · 757 participantsLow
Idrabiotaparinux vs idraparinux
Major bleeding during the initial treatment ‐ not reported · people > 18 years of age with a diagnosed deep vein thrombosis
Pentasaccharides for the treatment of deep vein thrombosis (2017) · Cochrane
no estimate extractedNRNo studies
Idrabiotaparinux vs idraparinux
Major bleeding · people > 18 years of age with a diagnosed deep vein thrombosis
Pentasaccharides for the treatment of deep vein thrombosis (2017) · Cochrane
RR 0.21 [0.06, 0.71]1 study · 755 participantsLow
Hand‐assisted laparoscopic repair vs EVAR
In‐hospital mortality · People undergoing elective abdominal aortic aneurysm repair
Laparoscopic surgery for elective abdominal aortic aneurysm repair (2017) · Cochrane
no estimate extracted1 study · 100 participantsLow
Hand‐assisted laparoscopic repair vs EVAR
Operative time (minutes) · People undergoing elective abdominal aortic aneurysm repair
Laparoscopic surgery for elective abdominal aortic aneurysm repair (2017) · Cochrane
no estimate extracted1 study · 100 participantsLow
Hand‐assisted laparoscopic repair vs EVAR
Major complications ‐ lower limb ischaemia (up to 12 months) · People undergoing elective abdominal aortic aneurysm repair
Laparoscopic surgery for elective abdominal aortic aneurysm repair (2017) · Cochrane
RR 0.5 [0.05, 5.34]1 study · 100 participantsLow
Hand‐assisted laparoscopic repair vs EVAR
Long‐term complications (12 months or longer if reported) · People undergoing elective abdominal aortic aneurysm repair
Laparoscopic surgery for elective abdominal aortic aneurysm repair (2017) · Cochrane
no estimate extractedNRNo studies
Hand‐assisted laparoscopic repair vs EVAR
All‐cause mortality/survival (> 30 days) · People undergoing elective abdominal aortic aneurysm repair
Laparoscopic surgery for elective abdominal aortic aneurysm repair (2017) · Cochrane
no estimate extractedNRNo studies
Hand‐assisted laparoscopic repair vs EVAR
Length of ICU stay (days) · People undergoing elective abdominal aortic aneurysm repair
Laparoscopic surgery for elective abdominal aortic aneurysm repair (2017) · Cochrane
no estimate extractedNRNo studies
Hand‐assisted laparoscopic repair vs EVAR
Overall length of hospital stay (days) · People undergoing elective abdominal aortic aneurysm repair
Laparoscopic surgery for elective abdominal aortic aneurysm repair (2017) · Cochrane
no estimate extracted1 study · 100 participantsLow
Intervention NR
Number of attacks · primary Raynaud's phenomenon
Calcium channel blockers for primary Raynaud's phenomenon (2016) · Cochrane
no estimate extracted7 studies · 296 participantsModerate
Intervention NR
Duration of attacks · primary Raynaud's phenomenon
Calcium channel blockers for primary Raynaud's phenomenon (2016) · Cochrane
no estimate extracted1 study · 16 participantsVery low
Intervention NR
Severity scores · primary Raynaud's phenomenon
Calcium channel blockers for primary Raynaud's phenomenon (2016) · Cochrane
no estimate extracted6 studies · 291 participantsHigh