Adverse events · Adults with periodontitis (chronic and aggressive)
It is very uncertain whether azithromycin + SRP changes adverse events compared with SRP (very low certainty).
1 finding from 1 review
1 study reported diarrhoea, headache or dizziness, metallic taste, and general unwellness by 4 participants from the intervention group and 3 from the control group. In 1 study none of the participants reported any…
2 studies · 110 participants
Very low
Permanent altered tongue, chin, or lip sensation · Adults with mandibular third molars requiring removal
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events · Adults with periodontitis (chronic and aggressive)
It is very uncertain whether amoxicillin + metronidazole + SRP changes adverse events compared with SRP (very low certainty).
1 finding from 1 review
Most common adverse events were mild gastrointestinal disturbances, nausea and vomiting, metallic taste, and diarrhoea in the intervention group. Control group reported adverse events like hypothermia, mild…
2 studies · 389 participants
Very low
Adverse events · Adults with aggressive periodontitis
The review found no eligible studies for this question.
1 finding from 1 review
Clinical attachment level (CAL) · Adults with chronic periodontitis
Levofloxacin + SRP led to lower clinical attachment level (CAL) compared with SRP; GRADE not reported.
2 findings from 1 review
Patient-reported quality of life changes · Adults with periodontitis (chronic and aggressive)
The review found no eligible studies for this question.
1 finding from 1 review
Percentage of bleeding on probing (BOP) · Adults with aggressive periodontitis
The review found no eligible studies for this question.
1 finding from 1 review
Adverse effects · Adults with mandibular third molars requiring removal
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Permanent altered tongue, chin, or lip sensation · Adults with mandibular third molars requiring removal
It is very uncertain whether triangular flap changes permanent altered tongue, chin, or lip sensation compared with envelope flap (very low certainty).
1 finding from 1 review
Adverse effects (reactionary bleeding) · Adults with mandibular third molars requiring removal
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Postoperative pain (mean) · Adults with mandibular third molars requiring removal
Primary (complete) wound closure led to higher postoperative pain (mean) compared with secondary (partial) wound closure; GRADE not reported.
1 finding from 1 review
Presence of dry socket · Adults with mandibular third molars requiring removal
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Permanent altered tongue, chin, or lip sensation · Adults with mandibular third molars requiring removal
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Permanent altered tongue, chin, or lip sensation · Adults with mandibular third molars requiring removal
It is very uncertain whether lingual nerve retractor (subperiosteal or Free's) changes permanent altered tongue, chin, or lip sensation compared with no retractor (very low certainty).
1 finding from 1 review
Probing pocket depth · Adults with aggressive periodontitis
Amoxicillin + clavulanate + SRP showed no clear difference in probing pocket depth compared with tetracycline + SRP; GRADE not reported.
1 finding from 1 review
MD -0.40 [-1.11, 0.31]
1 study · 8 participants
GRADE not reported
Percentage of closed pockets · Adults with aggressive periodontitis
The review found no eligible studies for this question.
1 finding from 1 review
Presence of dry socket · Adults with mandibular third molars requiring removal
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Probing pocket depth · Adults with chronic periodontitis
Cefixime + SRP showed no clear difference in probing pocket depth compared with SRP; GRADE not reported.
1 finding from 1 review
Adverse events · Adults with aggressive periodontitis
Doxycycline + SRP showed no clear difference in adverse events compared with amoxicillin + metronidazole + SRP; GRADE not reported.
1 finding from 1 review
Postoperative pain · Adults with mandibular third molars requiring removal
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found