Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,097 questions · 1,119 findings · 70 reviews · Kidney and Transplant

No studies found 271 · 24.2%GRADE not reported 17 · 1.5%Very low 271 · 24.2%Low 349 · 31.2%Moderate 182 · 16.3%High 29 · 2.6%

Angiotensin receptor blockers (ARBs) vs placebo or no treatment

Cardiovascular mortality · people with diabetes and kidney disease

Angiotensin receptor blockers showed no clear difference in cardiovascular death Median compared with placebo or no treatment (low certainty).

1 finding from 1 review

Summary of findings table ‐ High sodium dialysate vs standard sodium dialysate

Dialysis dysequilibrium syndrome · patients requiring haemodialysis

It is very uncertain whether summary of findings table ‐ High sodium dialysate changes dialysis dysequilibrium syndrome compared with standard sodium dialysate (very low certainty).

1 finding from 1 review

Summary of findings table ‐ High sodium dialysate vs standard sodium dialysate

Severe dialysis dysequilibrium syndrome · patients requiring haemodialysis

It is very uncertain whether summary of findings table ‐ High sodium dialysate changes severe dialysis dysequilibrium syndrome compared with standard sodium dialysate (very low certainty).

1 finding from 1 review