Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,721 questions · 19,640 findings · 2,039 reviews · Headline outcomes only

No studies found 3,754 · 19.1%GRADE not reported 1,273 · 6.5%Very low 4,859 · 24.7%Low 5,568 · 28.4%Moderate 3,240 · 16.5%High 946 · 4.8%

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MDA vs no MDA

Parasitaemia prevalence · People of all ages living in an area with moderate to high endemicity of P falciparum malaria (≥ 10% prevalence)

MDA showed no clear difference in parasitaemia prevalence compared with no MDA (low certainty).

1 finding from 1 review

MDA vs no MDA

Parasitaemia prevalence · People of all ages living in an area with very low to low endemicity of P falciparum malaria ( < 10% prevalence)

It is very uncertain whether MDA changes parasitaemia prevalence compared with no MDA (very low certainty).

6 findings from 1 review
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MDA vs no MDA

Parasitaemia prevalence · People of all ages living in an area with very low to low endemicity of P vivax malaria (< 10% prevalence)

MDA may leads to lower parasitaemia prevalence compared with no MDA (low certainty).

6 findings from 1 review
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Community professional‐led interventions vs no care

Depression symptoms (1 to 6 months post intervention) Beck Depression Inventorye; Oxford Measure of Psychosocial Adjustmentd (higher score = higher severity) · children/adolescents with post‐traumatic stress and related depressive/anxiety symptoms
1 finding from 1 review

Lay health worker‐led psychosocial interventions vs enhanced usual care

Depression recovery ‐ intermediate term (1 to 6 months post intervention) · women with perinatal depression

Lay health worker‐led psychosocial interventions may leads to higher recovery from depression ‐ intermediate term (1 to 6 months post… compared with enhanced usual care (low certainty).

1 finding from 1 review

Lay health worker‐led psychosocial interventions vs enhanced usual care

Depression symptoms ‐ intermediate term (1 to 6 months post intervention) GHQ‐12a; PHQ‐9d,e,f; self‐reporting questionnaireh (higher score = higher severity) · women with perinatal depression
1 finding from 1 review