Iron deficiency at term (as defined by trialists, based on any indicator of iron status at 37 wk gestation or more) · pregnant women
(Maternal outcomes) Any supplements containing iron may leads to lower maternal iron deficiency at term (as defined by as defined by… compared with same supplements without iron or no treatment/placebo (no iron or… (low certainty).
1 finding from 1 review
Maternal death · pregnant women
It is very uncertain whether (Maternal outcomes) Any supplements containing iron changes maternal death (death while pregnant or within 42 days of… compared with same supplements without iron or no treatment/placebo (no iron or… (very low certainty).
1 finding from 1 review
Side effects (any reported throughout the intervention period) (ALL) · pregnant women
It is very uncertain whether (Maternal outcomes) Any supplements containing iron changes side effects (any reported throughout the intervention period) (ALL) compared with same supplements without iron or no treatment/placebo (no iron or… (very low certainty).
1 finding from 1 review
Blood loss > 400 mL or > 500 mL · pregnant women undergoing vaginal or caesarean birth who received TA for the prevention of postpartum haemorrhage
Tranexamic acid probably leads to lower blood loss > 400 mL or > 500 mL compared with placebo/no treatment (moderate certainty).
1 finding from 1 review
Blood loss > 1000 mL · pregnant women undergoing vaginal or caesarean birth who received TA for the prevention of postpartum haemorrhage
Tranexamic acid probably leads to lower blood loss > 1000 mL compared with placebo/no treatment (moderate certainty).
1 finding from 1 review
Mean blood loss (mL) · pregnant women undergoing vaginal or caesarean birth who received TA for the prevention of postpartum haemorrhage
1 finding from 1 review
Use of additional medical interventions to control PPH · pregnant women undergoing vaginal or caesarean birth who received TA for the prevention of postpartum haemorrhage
Tranexamic acid probably leads to lower use of additional medical interventions to control PPH compared with placebo/no treatment (moderate certainty).
1 finding from 1 review
Serious maternal morbidity or death · pregnant women undergoing vaginal or caesarean birth who received TA for the prevention of postpartum haemorrhage
1 finding from 1 review
Side effects · pregnant women undergoing vaginal or caesarean birth who received TA for the prevention of postpartum haemorrhage
Tranexamic acid probably leads to higher side effects compared with placebo/no treatment (moderate certainty).
1 finding from 1 review
Thromboembolic events · pregnant women undergoing vaginal or caesarean birth who received TA for the prevention of postpartum haemorrhage
Tranexamic acid showed no clear difference in thromboembolic events compared with placebo/no treatment (low certainty).
1 finding from 1 review
Language development ‐ Beyond 24 months · Breastfeeding mothers
1 finding from 1 review
Intelligence or problem‐solving ability ‐ Beyond 24 months · Breastfeeding mothers
1 finding from 1 review
Psychomotor development · Breastfeeding mothers
1 finding from 1 review
Attention · Breastfeeding mothers
1 finding from 1 review
Visual acuity · Breastfeeding mothers
1 finding from 1 review
Child weight ‐ Long term beyond 24 months · Breastfeeding mothers
1 finding from 1 review
Neural tube defects (All) · all women who become pregnant or were 12 or less weeks' pregnant at the time of the intervention
Supplementation with folate leads to lower neural tube defects (All) compared with no intervention, placebo or other micronutrients without folate… (high certainty).
1 finding from 1 review
Miscarriage · all women who become pregnant or were 12 or less weeks' pregnant at the time of the intervention
Supplementation with folate showed no clear difference in miscarriage (All) compared with no intervention, placebo or other micronutrients without folate… (moderate certainty).
1 finding from 1 review
Cleft lip (All) · all women who become pregnant or were 12 or less weeks' pregnant at the time of the intervention
Supplementation with folate showed no clear difference in cleft lip (All) compared with no intervention, placebo or other micronutrients without folate… (low certainty).
1 finding from 1 review
Cleft palate (All) · all women who become pregnant or were 12 or less weeks' pregnant at the time of the intervention
Supplementation with folate showed no clear difference in cleft palate (All) compared with no intervention, placebo or other micronutrients without folate… (low certainty).
1 finding from 1 review